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MA33291B1 - Pipéridines substituées - Google Patents

Pipéridines substituées

Info

Publication number
MA33291B1
MA33291B1 MA34376A MA34376A MA33291B1 MA 33291 B1 MA33291 B1 MA 33291B1 MA 34376 A MA34376 A MA 34376A MA 34376 A MA34376 A MA 34376A MA 33291 B1 MA33291 B1 MA 33291B1
Authority
MA
Morocco
Prior art keywords
diseases
substituted piperidines
treating
preventing
piperidines
Prior art date
Application number
MA34376A
Other languages
English (en)
Inventor
Dirk Heimbach
Susanne Roehrig
Grande Yolanda Cancho
Eckhard Bender
Katja Zimmermann
Anja Buchmueller
Christoph Gerdes
Mark Jean Gnoth
Kersten Matthias Gericke
Mario Jeske
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of MA33291B1 publication Critical patent/MA33291B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne de nouvelles pipéridines substituées, des procédés pour les produire, leur utilisation pour traiter et/ou prévenir des maladies, ainsi que leur utilisation pour produire des médicaments pour traiter et/ou prévenir des maladies, en particulier des maladies cardiovasculaires et des maladies tumorales.
MA34376A 2009-05-27 2010-05-18 Pipéridines substituées MA33291B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009022894A DE102009022894A1 (de) 2009-05-27 2009-05-27 Substituierte Piperidine
PCT/EP2010/003024 WO2010136138A1 (fr) 2009-05-27 2010-05-18 Pipéridines substituées

Publications (1)

Publication Number Publication Date
MA33291B1 true MA33291B1 (fr) 2012-05-02

Family

ID=42537882

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34376A MA33291B1 (fr) 2009-05-27 2010-05-18 Pipéridines substituées

Country Status (28)

Country Link
US (3) US8440657B2 (fr)
EP (1) EP2435431A1 (fr)
JP (1) JP5728687B2 (fr)
KR (1) KR20120024652A (fr)
CN (1) CN102482270B (fr)
AR (1) AR076709A1 (fr)
AU (1) AU2010252339B2 (fr)
BR (1) BRPI1012775A2 (fr)
CA (1) CA2763386A1 (fr)
CO (1) CO6470822A2 (fr)
CR (1) CR20110627A (fr)
CU (1) CU24011B1 (fr)
DE (1) DE102009022894A1 (fr)
EA (1) EA021944B1 (fr)
HN (1) HN2011003102A (fr)
IL (1) IL215903A0 (fr)
MA (1) MA33291B1 (fr)
MX (1) MX2011012507A (fr)
MY (1) MY166555A (fr)
NZ (1) NZ596621A (fr)
PE (1) PE20120402A1 (fr)
SG (1) SG175759A1 (fr)
TN (1) TN2011000596A1 (fr)
TW (1) TWI464166B (fr)
UA (1) UA107576C2 (fr)
UY (1) UY32652A (fr)
WO (1) WO2010136138A1 (fr)
ZA (1) ZA201108609B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009014484A1 (de) 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
UA115133C2 (uk) 2011-10-07 2017-09-25 Такеда Фармасьютікал Компані Лімітед Сполуки 1-арилкарбоніл-4-оксипіперидину, придатні для лікування нейродегенеративних захворювань
JP5900182B2 (ja) * 2012-06-21 2016-04-06 セントラル硝子株式会社 α，α−ジフルオロ芳香族化合物の製造方法
JP6197348B2 (ja) * 2013-04-25 2017-09-20 セントラル硝子株式会社 α，α−ジフルオロ芳香族化合物の保存安定性の向上方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767144A (en) 1994-08-19 1998-06-16 Abbott Laboratories Endothelin antagonists
WO1997036873A1 (fr) 1996-04-03 1997-10-09 Merck & Co., Inc. Piperidines, pyrrolidines et hexahydro-1h-azepines declenchant la liberation de l'hormone de croissance
US6403612B2 (en) 2000-01-31 2002-06-11 Merck & Co., Inc. Thrombin receptor antagonists
UA75980C2 (en) 2001-10-15 2006-06-15 Janssen Pharmaceutica Nv Substituted 4-pheny1-4-[1h-imidazol-2-yl] piperidine derivative for reducing ischaemic damages
DE10238113A1 (de) * 2001-12-11 2003-06-18 Bayer Ag Substituierte 2-Thio-3,5-dicyano-4-phenyl-6-aminopyridine und ihre Verwendung
KR20070024639A (ko) 2004-06-24 2007-03-02 인사이트 산 디에고 인코포레이티드 아미도 화합물 및 약제로서의 이의 용도
JP2008504279A (ja) 2004-06-24 2008-02-14 インサイト・コーポレイション アミド化合物およびその医薬としての使用
CA2570637A1 (fr) 2004-06-24 2006-02-02 Wenqing Yao Piperidines a substitution n et utilisation de ces dernieres en tant que substances pharmaceutiques
TW200626156A (en) 2004-08-10 2006-08-01 Incyte Corp Amido compounds and their use as pharmaceuticals
DE102004042607A1 (de) * 2004-09-03 2006-03-09 Bayer Healthcare Ag Substituierte Phenylaminothiazole und ihre Verwendung
DE102004045796A1 (de) 2004-09-22 2006-03-23 Merck Patent Gmbh Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung
EP1705960A1 (fr) 2005-03-21 2006-09-27 IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. Lampe électroluminescente
JP2009508963A (ja) 2005-09-21 2009-03-05 インサイト・コーポレイション アミド化合物および医薬組成物としてのその使用
US20070197530A1 (en) 2006-01-31 2007-08-23 Yun-Long Li Amido compounds and their use as pharmaceuticals
WO2007101270A1 (fr) 2006-03-02 2007-09-07 Incyte Corporation MODULATEURS DE LA 11β-HYDROXYSTEROIDE DESHYDROGENASE DE TYPE 1, COMPOSITIONS PHARMACEUTIQUES LES COMPRENANT ET PROCEDE D'UTILISATION DESDITS MODULATEURS
EP2013163A1 (fr) 2006-05-01 2009-01-14 Incyte Corporation Urées tétrasubstituées modulateurs de la 11-beta hydroxyl stéroïd déshydrogénase de type 1
CN101932577B (zh) 2007-11-30 2013-07-17 拜耳知识产权有限责任公司 杂芳基取代的哌啶
DE102009014484A1 (de) 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022895A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022892A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022897A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine

Also Published As

Publication number Publication date
US8202862B2 (en) 2012-06-19
EA201190313A1 (ru) 2012-05-30
NZ596621A (en) 2013-12-20
ZA201108609B (en) 2013-02-27
TWI464166B (zh) 2014-12-11
US8440657B2 (en) 2013-05-14
BRPI1012775A2 (pt) 2019-09-24
IL215903A0 (en) 2012-01-31
AU2010252339B2 (en) 2014-10-23
US20100305111A1 (en) 2010-12-02
UY32652A (es) 2010-12-31
CN102482270A (zh) 2012-05-30
HK1171450A1 (en) 2013-03-28
JP2012528089A (ja) 2012-11-12
SG175759A1 (en) 2011-12-29
TW201107319A (en) 2011-03-01
CU20110214A7 (es) 2012-03-15
EP2435431A1 (fr) 2012-04-04
CO6470822A2 (es) 2012-06-29
US20120135985A1 (en) 2012-05-31
MX2011012507A (es) 2011-12-14
CU24011B1 (es) 2014-06-27
UA107576C2 (ru) 2015-01-26
CR20110627A (es) 2012-03-22
KR20120024652A (ko) 2012-03-14
AR076709A1 (es) 2011-06-29
TN2011000596A1 (en) 2013-05-24
AU2010252339A1 (en) 2011-12-08
EA021944B1 (ru) 2015-10-30
JP5728687B2 (ja) 2015-06-03
HN2011003102A (es) 2015-02-23
CA2763386A1 (fr) 2010-12-02
WO2010136138A1 (fr) 2010-12-02
US20130252948A1 (en) 2013-09-26
MY166555A (en) 2018-07-16
PE20120402A1 (es) 2012-04-18
DE102009022894A1 (de) 2010-12-02
CN102482270B (zh) 2015-02-25

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