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MA32687B1 - Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale - Google Patents

Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale

Info

Publication number
MA32687B1
MA32687B1 MA33736A MA33736A MA32687B1 MA 32687 B1 MA32687 B1 MA 32687B1 MA 33736 A MA33736 A MA 33736A MA 33736 A MA33736 A MA 33736A MA 32687 B1 MA32687 B1 MA 32687B1
Authority
MA
Morocco
Prior art keywords
modified release
skin
application
vaginal mucosa
emulsions
Prior art date
Application number
MA33736A
Other languages
Arabic (ar)
English (en)
Inventor
Emanuela Mura
Federico Mailland
Daniela Ceriani
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40340663&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32687(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of MA32687B1 publication Critical patent/MA32687B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/345—Nitrofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)

Abstract

La présente invention concerne des émulsions huile dans l'eau à libération modifiée qui délivrent des médicaments à un tissu cible. Les émulsions selon la présente invention contiennent le principe actif lipophile complètement dissous dans la phase interne hydrophobe stabilisée par un surfactant polymère. La présence de ce polymère autour des gouttelettes hydrophobes évite la migration du principe actif dans la phase hydrophile externe et, en conséquence, sa recristallisation.
MA33736A 2008-10-08 2011-04-01 Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale MA32687B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08166058A EP2174650A1 (fr) 2008-10-08 2008-10-08 Émulsions à libération modifiée pour une application sur la peau ou la muqueuse vaginale
PCT/EP2009/062190 WO2010040632A1 (fr) 2008-10-08 2009-09-21 Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale

Publications (1)

Publication Number Publication Date
MA32687B1 true MA32687B1 (fr) 2011-10-02

Family

ID=40340663

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33736A MA32687B1 (fr) 2008-10-08 2011-04-01 Emulsions à libération modifiée destinées à une application sur la peau ou la muqueuse vaginale

Country Status (19)

Country Link
US (1) US20110195944A1 (fr)
EP (2) EP2174650A1 (fr)
JP (1) JP2012505171A (fr)
KR (1) KR20110067115A (fr)
CN (1) CN102170862A (fr)
AR (1) AR073801A1 (fr)
AU (1) AU2009301275A1 (fr)
BR (1) BRPI0920565A2 (fr)
CA (1) CA2737255A1 (fr)
CL (1) CL2011000767A1 (fr)
CO (1) CO6361898A2 (fr)
EA (1) EA201170555A1 (fr)
IL (1) IL211681A0 (fr)
MA (1) MA32687B1 (fr)
MX (1) MX2011003696A (fr)
NZ (1) NZ591919A (fr)
PE (1) PE20110449A1 (fr)
WO (1) WO2010040632A1 (fr)
ZA (1) ZA201101818B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2612511T3 (es) * 2011-01-27 2017-05-17 Glaxosmithkline Biologicals Sa Nanoemulsiones de adyuvante con inhibidores de cristalización
JP6076962B2 (ja) * 2011-04-01 2017-02-08 フロリダ大学 リサーチファウンデーション インコーポレイティッド 治療薬を局所送達するための感熱性を有する粘膜付着性または皮膚粘着性の浸透促進剤
DE102011076869A1 (de) * 2011-06-01 2012-12-06 Beiersdorf Ag Emulsionszubereitungen mit verbesserten rheologischen Eigenschaften
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP3936133A1 (fr) 2011-11-23 2022-01-12 TherapeuticsMD, Inc. Préparations et thérapies de substitution pour hormonothérapie naturelle combinée
WO2013093823A2 (fr) 2011-12-20 2013-06-27 Vyome Biosciences Pvt Ltd Compositions d'huile à usage topique pour le traitement des infections fongiques
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
KR101862448B1 (ko) * 2013-04-12 2018-05-29 바이옴 바이오사이언스 피브이티. 엘티디. 항균제의 조성물과 제제, 그 공정, 및 세균 감염을 치료하는 방법
AU2015229421B2 (en) * 2014-03-12 2020-06-04 Allergan Therapeutics LLC Low-dose estradiol cream
US10206932B2 (en) 2014-05-22 2019-02-19 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
CA3020153A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Composition pharmaceutique d'hormone steroide
MX384337B (es) * 2016-10-13 2025-03-14 Catalent Uk Swindon Zydis Ltd Composiciones farmacéuticas liofilizadas para suministro vaginal.
KR20200019735A (ko) * 2017-06-22 2020-02-24 비라말 리미티드 약물 전달을 위한 조성물 및 그의 사용 방법
WO2019213473A1 (fr) 2018-05-04 2019-11-07 The Procter & Gamble Company Compositions et méthodes de traitement de la sécheresse vaginale
EP3659583B1 (fr) 2018-11-30 2023-06-07 Viramal Limited Procédé de préparation d'un agent coagulant, agent coagulant ainsi obtenu et utilisation de cet agent coagulant

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4384409B2 (ja) * 2000-12-05 2009-12-16 チルドレンズ・ホスピタル・ロス・アンジエルス バイオアベイラビリティが増加したフェンレチニドの医薬組成物、およびその使用方法
WO2003084538A1 (fr) * 2002-04-04 2003-10-16 Medicis Pharmaceutical Corporation Methodes de traitement de l'acne rosacee au moyen de pyridones
US20060233721A1 (en) * 2002-10-25 2006-10-19 Foamix Ltd. Foam containing unique oil globules
US20060018937A1 (en) * 2002-10-25 2006-01-26 Foamix Ltd. Steroid kit and foamable composition and uses thereof
US20040087564A1 (en) * 2002-10-31 2004-05-06 Wright D. Craig Delivery composition and method
EP1919449A2 (fr) * 2005-06-07 2008-05-14 Foamix Ltd. Kit et composition antibiotiques et leurs utilisations
US20070071705A1 (en) * 2005-09-29 2007-03-29 De Oliveira Monica A M Topical anti-microbial compositions
US20080075745A1 (en) * 2006-09-21 2008-03-27 Glenmark Pharmaceuticals Limited Topical pharmaceutical compositions containing ciclopirox or a pharmaceutically acceptable salt thereof

Also Published As

Publication number Publication date
BRPI0920565A2 (pt) 2015-12-29
MX2011003696A (es) 2011-06-20
AR073801A1 (es) 2010-12-01
EP2331065A1 (fr) 2011-06-15
US20110195944A1 (en) 2011-08-11
CO6361898A2 (es) 2012-01-20
NZ591919A (en) 2012-09-28
CN102170862A (zh) 2011-08-31
IL211681A0 (en) 2011-06-30
ZA201101818B (en) 2012-05-30
AU2009301275A2 (en) 2011-04-28
JP2012505171A (ja) 2012-03-01
CA2737255A1 (fr) 2010-04-15
CL2011000767A1 (es) 2011-06-17
EP2174650A1 (fr) 2010-04-14
PE20110449A1 (es) 2011-07-07
EA201170555A1 (ru) 2011-12-30
KR20110067115A (ko) 2011-06-21
AU2009301275A1 (en) 2010-04-15
WO2010040632A1 (fr) 2010-04-15

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