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MA30569B1 - Vaccin recombinant contre le virus de la fievre catarrhale ovine - Google Patents

Vaccin recombinant contre le virus de la fievre catarrhale ovine

Info

Publication number
MA30569B1
MA30569B1 MA31522A MA31522A MA30569B1 MA 30569 B1 MA30569 B1 MA 30569B1 MA 31522 A MA31522 A MA 31522A MA 31522 A MA31522 A MA 31522A MA 30569 B1 MA30569 B1 MA 30569B1
Authority
MA
Morocco
Prior art keywords
btv
virus
composition
fishery
vaccine against
Prior art date
Application number
MA31522A
Other languages
English (en)
Inventor
Jean Christophe Francis Audonnet
Kemal Karaca
Jiansheng Yao
Nigel James Maclachlan
Original Assignee
Merial Ltd
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, Univ California filed Critical Merial Ltd
Publication of MA30569B1 publication Critical patent/MA30569B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)

Abstract

La présente invention concerne une composition immunogène ou vaccinale pour provoquer une réponse immunitaire ou une réponse immunitaire protectrice contre les orbivirus, plus spécifiquement le virus de la fièvre catarrhale du mouton (BTV, bluetongue virus) chez un animal sensible à l'infection par le BTV. La composition peut inclure un véhicule ou un excipient pharmaceutiquement ou vétérinairement acceptables, et un vecteur. Le vecteur peut contenir une ou plusieurs molécules d'acide nucléique hétérologues, exprimer in vivo un antigène, un immunogène ou un épitope du BTV de l'animal, par exemple VP2 du BTV ; VP2 et VP5 du BTV ; VP2 et VP5 et VP3 du BTV et/ou VP7 du BTV. La composition peut contenir un adjuvant, comme un carbomère. Des procédés pour fabriquer et utiliser cette composition, incluant des régimes de vaccination avec primo-vaccination rappel, et incluant un diagnostic différentiel, sont aussi envisagés.
MA31522A 2006-06-01 2008-12-26 Vaccin recombinant contre le virus de la fievre catarrhale ovine MA30569B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/444,698 US7862821B2 (en) 2006-06-01 2006-06-01 Recombinant vaccine against bluetongue virus

Publications (1)

Publication Number Publication Date
MA30569B1 true MA30569B1 (fr) 2009-07-01

Family

ID=38790493

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31522A MA30569B1 (fr) 2006-06-01 2008-12-26 Vaccin recombinant contre le virus de la fievre catarrhale ovine

Country Status (16)

Country Link
US (1) US7862821B2 (fr)
EP (2) EP2816057B1 (fr)
CN (2) CN101754975B (fr)
AR (1) AR061152A1 (fr)
AU (1) AU2007293474C9 (fr)
BR (1) BRPI0712191A2 (fr)
CA (1) CA2653696C (fr)
ES (1) ES2623138T3 (fr)
IL (1) IL195641A (fr)
MA (1) MA30569B1 (fr)
NZ (1) NZ573435A (fr)
RU (1) RU2446823C2 (fr)
TW (1) TWI399213B (fr)
UY (1) UY30385A1 (fr)
WO (1) WO2008030282A2 (fr)
ZA (1) ZA200810826B (fr)

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CN103305472A (zh) * 2013-06-18 2013-09-18 中国农业科学院哈尔滨兽医研究所 抗蓝舌病病毒血清1型vp2蛋白的单克隆抗体btv1-3e8及其识别的b细胞表位多肽与应用
CN103305473B (zh) * 2013-06-18 2015-01-07 中国农业科学院哈尔滨兽医研究所 抗蓝舌病病毒血清1型vp2蛋白的单克隆抗体btv1-4b6及其识别的b细胞表位多肽与应用
CN104258138A (zh) * 2014-09-28 2015-01-07 山东新希望六和集团有限公司 一种用于治疗牛蓝舌病的药物组合物及其制备方法
JP7245260B2 (ja) * 2018-03-19 2023-03-23 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Ｅｈｖ挿入部位ｕｌ４３
CN110551634A (zh) * 2019-09-04 2019-12-10 中国农业科学院兰州兽医研究所 一种山羊支原体山羊肺炎亚种分离培养方法
CN110551653A (zh) * 2019-09-04 2019-12-10 中国农业科学院兰州兽医研究所 一种无血清制备牛支原体抗原的方法
CN113308441B (zh) * 2021-06-02 2022-05-10 华中农业大学 一株猫疱疹病毒i型病毒株及其应用

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AU2007293474B2 (en) 2012-07-19
IL195641A (en) 2013-12-31
NZ573435A (en) 2011-09-30
CN103143034A (zh) 2013-06-12
EP2816057A1 (fr) 2014-12-24
AU2007293474A1 (en) 2008-03-13
IL195641A0 (en) 2011-08-01
AR061152A1 (es) 2008-08-06
HK1200180A1 (en) 2015-07-31
TWI399213B (zh) 2013-06-21
CN101754975A (zh) 2010-06-23
UY30385A1 (es) 2008-01-02
ZA200810826B (en) 2009-11-25
US7862821B2 (en) 2011-01-04
EP2816057B1 (fr) 2017-02-01
ES2623138T3 (es) 2017-07-10
AU2007293474C9 (en) 2014-09-18
CA2653696C (fr) 2017-10-24
CN101754975B (zh) 2013-01-02
US20070280960A1 (en) 2007-12-06
BRPI0712191A2 (pt) 2012-03-06
TW200810779A (en) 2008-03-01
WO2008030282A3 (fr) 2009-12-17
EP2029622A2 (fr) 2009-03-04
CA2653696A1 (fr) 2008-03-13
RU2008152064A (ru) 2010-07-20
RU2446823C2 (ru) 2012-04-10
AU2007293474C1 (en) 2014-06-05

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