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MA29595B1 - Anticorps anti-cd40 humanises et procedes d'utilisation - Google Patents

Anticorps anti-cd40 humanises et procedes d'utilisation

Info

Publication number
MA29595B1
MA29595B1 MA30474A MA30474A MA29595B1 MA 29595 B1 MA29595 B1 MA 29595B1 MA 30474 A MA30474 A MA 30474A MA 30474 A MA30474 A MA 30474A MA 29595 B1 MA29595 B1 MA 29595B1
Authority
MA
Morocco
Prior art keywords
antibodies
methods
humanized anti
antigen
expression
Prior art date
Application number
MA30474A
Other languages
English (en)
Inventor
Leonard G Presta
Lori Y O'connell
Svetlana O Doronina
Original Assignee
Seattle Genetics Inc
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37452957&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA29595(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Seattle Genetics Inc, Genentech Inc filed Critical Seattle Genetics Inc
Publication of MA29595B1 publication Critical patent/MA29595B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ANTICORPS ANTI-CD40 HUMANISÉS ET FRAGMENTS DE LIAISON À L'ANTIGÈNE ET PROCÉDÉS POUR LE TRAITEMENT DE MALADIES CARACTÉRISÉES PAR L'EXPRESSION D'ANTIGÈNE CD40.
MA30474A 2005-05-26 2007-12-11 Anticorps anti-cd40 humanises et procedes d'utilisation MA29595B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68485305P 2005-05-26 2005-05-26

Publications (1)

Publication Number Publication Date
MA29595B1 true MA29595B1 (fr) 2008-07-01

Family

ID=37452957

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30474A MA29595B1 (fr) 2005-05-26 2007-12-11 Anticorps anti-cd40 humanises et procedes d'utilisation

Country Status (19)

Country Link
US (4) US8303955B2 (fr)
EP (1) EP1885399B1 (fr)
JP (1) JP5027804B2 (fr)
KR (1) KR100991010B1 (fr)
CN (1) CN101237882B (fr)
AT (1) ATE485057T1 (fr)
AU (1) AU2006249305B2 (fr)
BR (1) BRPI0610470A2 (fr)
CA (1) CA2609269C (fr)
CR (1) CR9562A (fr)
DE (1) DE602006017690D1 (fr)
EC (1) ECSP078026A (fr)
ES (1) ES2354865T3 (fr)
IL (1) IL187594A0 (fr)
MA (1) MA29595B1 (fr)
NO (1) NO341793B1 (fr)
PL (1) PL1885399T3 (fr)
RU (1) RU2407544C2 (fr)
WO (1) WO2006128103A2 (fr)

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EP2125893A2 (fr) * 2007-01-23 2009-12-02 Xencor, Inc. Anticorps cd40 optimisés et leurs procédés d'utilisation
CA2704499C (fr) 2007-11-07 2020-03-10 Genentech, Inc. Procedes et compositions pour evaluer la reactivite d'un lymphome lymphocytaire b a un traitement par anticorps anti-cd40
US8961991B2 (en) 2009-03-10 2015-02-24 Baylor Research Institute Anti-CD40 targeted fusion proteins
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CA3032548C (fr) 2009-03-10 2023-05-09 Baylor Research Institute Anticorps anti-cd40 et utilisations de ceux-ci
US9617600B2 (en) 2009-04-18 2017-04-11 Genentech, Inc. Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies
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AU2006249305B2 (en) 2012-10-18
JP2008541733A (ja) 2008-11-27
CN101237882A (zh) 2008-08-06
ECSP078026A (es) 2008-03-26
CN101237882B (zh) 2012-08-15
US20090181015A1 (en) 2009-07-16
PL1885399T3 (pl) 2011-04-29
RU2407544C2 (ru) 2010-12-27
IL187594A0 (en) 2008-03-20
EP1885399A4 (fr) 2009-04-22
KR100991010B1 (ko) 2010-10-29
EP1885399B1 (fr) 2010-10-20
WO2006128103A2 (fr) 2006-11-30
NO341793B1 (no) 2018-01-22
US20140193405A1 (en) 2014-07-10
US20130315900A1 (en) 2013-11-28
US8303955B2 (en) 2012-11-06
CR9562A (es) 2008-03-06
BRPI0610470A2 (pt) 2010-06-22
ATE485057T1 (de) 2010-11-15
CA2609269A1 (fr) 2006-11-30
CA2609269C (fr) 2014-08-05
US8492531B2 (en) 2013-07-23
US20130023047A1 (en) 2013-01-24
KR20080030958A (ko) 2008-04-07
JP5027804B2 (ja) 2012-09-19
NO20076404L (no) 2008-02-13
AU2006249305A1 (en) 2006-11-30
WO2006128103A3 (fr) 2007-01-18
EP1885399A2 (fr) 2008-02-13
RU2007148932A (ru) 2009-07-10
DE602006017690D1 (de) 2010-12-02
ES2354865T3 (es) 2011-03-18

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