MA26867A1 - Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés - Google Patents
Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composésInfo
- Publication number
- MA26867A1 MA26867A1 MA26735A MA26735A MA26867A1 MA 26867 A1 MA26867 A1 MA 26867A1 MA 26735 A MA26735 A MA 26735A MA 26735 A MA26735 A MA 26735A MA 26867 A1 MA26867 A1 MA 26867A1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- dicarboxylates
- diabetes
- preparation
- vascular diseases
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 208000019553 vascular disease Diseases 0.000 title abstract 2
- SDMBRCRVFFHJKR-UHFFFAOYSA-N 6-(5-carboxy-5-methylhexoxy)-2,2-dimethylhexanoic acid Chemical compound OC(=O)C(C)(C)CCCCOCCCCC(C)(C)C(O)=O SDMBRCRVFFHJKR-UHFFFAOYSA-N 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
DEPOSANT Société dite: WARNER-LAMBERTCOMPANY REVENDICATION DE PRIORITES US 25 Janvier 2000 60/177,823 "Ether-dicarboxylates de calcium, procédés pour leur préparation et traitement de maladies vasculaires et du diabète avec ces composés" Les produits de solvatation avec des alcools et l'eau du sel monocalcique d'acide 6-(5-carboxy-5-méthyi-hexyloxy)-2,2-diméthyl-hexanoïque sont cristallins et répondent à la formule (I), dans laquelle R1 représente H ou un groupe alkyle inférieur, et x est un nombre de 0 à 10, et sont utiles pour le traitement de la dyslipidémie.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17782300P | 2000-01-25 | 2000-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA26867A1 true MA26867A1 (fr) | 2004-12-20 |
Family
ID=22650106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA26735A MA26867A1 (fr) | 2000-01-25 | 2002-07-22 | Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés |
Country Status (39)
| Country | Link |
|---|---|
| EP (1) | EP1259474B1 (fr) |
| JP (1) | JP4750995B2 (fr) |
| KR (1) | KR20020073182A (fr) |
| CN (1) | CN1395555A (fr) |
| AP (1) | AP2002002587A0 (fr) |
| AR (1) | AR029436A1 (fr) |
| AT (1) | ATE431326T1 (fr) |
| AU (1) | AU2214001A (fr) |
| BG (1) | BG106851A (fr) |
| BR (1) | BR0107763A (fr) |
| CA (1) | CA2397960C (fr) |
| CO (1) | CO5261537A1 (fr) |
| CZ (1) | CZ20022474A3 (fr) |
| DE (1) | DE60138686D1 (fr) |
| DK (1) | DK1259474T3 (fr) |
| DZ (1) | DZ3239A1 (fr) |
| EA (1) | EA004862B1 (fr) |
| EE (1) | EE200200404A (fr) |
| ES (1) | ES2324281T3 (fr) |
| GE (1) | GEP20053428B (fr) |
| GT (1) | GT200100015A (fr) |
| HN (1) | HN2001000011A (fr) |
| HU (1) | HUP0204422A3 (fr) |
| IL (1) | IL150541A0 (fr) |
| IS (1) | IS6442A (fr) |
| MA (1) | MA26867A1 (fr) |
| MX (1) | MXPA02007223A (fr) |
| NO (1) | NO20023526L (fr) |
| NZ (1) | NZ519550A (fr) |
| OA (1) | OA12166A (fr) |
| PA (1) | PA8510601A1 (fr) |
| PE (1) | PE20011064A1 (fr) |
| PL (1) | PL357076A1 (fr) |
| SK (1) | SK10622002A3 (fr) |
| SV (1) | SV2002000290A (fr) |
| TN (1) | TNSN01013A1 (fr) |
| UY (1) | UY26550A1 (fr) |
| WO (1) | WO2001055078A1 (fr) |
| ZA (1) | ZA200205880B (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1045691T1 (en) * | 1997-12-12 | 2005-04-30 | Warner-Lambert Company Llc | Statin-carboxyalkylether combinations |
| KR20050058454A (ko) * | 2002-08-22 | 2005-06-16 | 워너-램버트 캄파니 엘엘씨 | 골관절염의 치료 방법 |
| KR20080007315A (ko) * | 2005-04-19 | 2008-01-18 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 비스[(2ｓ)-3-[3-[(2ｓ)-3-(4-클로로-2-시아노페녹시)-2-플루오로프로폭시]페닐]-2-이소프로폭시프로피온산]칼슘 및그 중간체 |
| US7816405B2 (en) | 2005-04-19 | 2010-10-19 | Eisai R&D Management Co., Ltd. | Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof |
| BR112017009876A2 (pt) * | 2014-11-14 | 2017-12-19 | Gemphire Therapeutics Inc | processos e intermediários para a preparação de éteres de dialcano terminados em ácido alfa,ômega-dicarboxílico |
| IL269884B2 (en) * | 2017-04-18 | 2023-09-01 | Gemphire Therapeutics Inc | Gamkaban its accepted pharmaceutical salts, their compositions and methods of their use |
| KR20210093900A (ko) * | 2018-10-18 | 2021-07-28 | 젬파이어 세러퓨틱스 인코포레이티드 | 젬카빈, 이의 약학적으로 허용가능한 염, 이의 조성물 및 이의 사용 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
| NZ503982A (en) | 1997-12-12 | 2002-03-28 | Warner Lambert Co | Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus |
-
2001
- 2001-01-11 NZ NZ519550A patent/NZ519550A/en unknown
- 2001-01-11 CN CN01804045A patent/CN1395555A/zh active Pending
- 2001-01-11 PL PL01357076A patent/PL357076A1/xx not_active Application Discontinuation
- 2001-01-11 KR KR1020027009519A patent/KR20020073182A/ko not_active Ceased
- 2001-01-11 IL IL15054101A patent/IL150541A0/xx unknown
- 2001-01-11 GE GE4872A patent/GEP20053428B/en unknown
- 2001-01-11 DE DE60138686T patent/DE60138686D1/de not_active Expired - Lifetime
- 2001-01-11 WO PCT/IB2001/000026 patent/WO2001055078A1/fr not_active Ceased
- 2001-01-11 JP JP2001555021A patent/JP4750995B2/ja not_active Expired - Fee Related
- 2001-01-11 OA OA1200200226A patent/OA12166A/en unknown
- 2001-01-11 ES ES01900037T patent/ES2324281T3/es not_active Expired - Lifetime
- 2001-01-11 CA CA002397960A patent/CA2397960C/fr not_active Expired - Lifetime
- 2001-01-11 AP APAP/P/2002/002587A patent/AP2002002587A0/en unknown
- 2001-01-11 BR BR0107763-5A patent/BR0107763A/pt not_active IP Right Cessation
- 2001-01-11 EP EP01900037A patent/EP1259474B1/fr not_active Expired - Lifetime
- 2001-01-11 AU AU22140/01A patent/AU2214001A/en not_active Abandoned
- 2001-01-11 MX MXPA02007223A patent/MXPA02007223A/es active IP Right Grant
- 2001-01-11 SK SK1062-2002A patent/SK10622002A3/sk not_active Application Discontinuation
- 2001-01-11 DK DK01900037T patent/DK1259474T3/da active
- 2001-01-11 AT AT01900037T patent/ATE431326T1/de not_active IP Right Cessation
- 2001-01-11 CZ CZ20022474A patent/CZ20022474A3/cs unknown
- 2001-01-11 HU HU0204422A patent/HUP0204422A3/hu unknown
- 2001-01-11 DZ DZ013239A patent/DZ3239A1/fr active
- 2001-01-11 EE EEP200200404A patent/EE200200404A/xx unknown
- 2001-01-11 EA EA200200641A patent/EA004862B1/ru not_active IP Right Cessation
- 2001-01-22 UY UY26550A patent/UY26550A1/es not_active Application Discontinuation
- 2001-01-22 SV SV2001000290A patent/SV2002000290A/es not_active Application Discontinuation
- 2001-01-23 GT GT200100015A patent/GT200100015A/es unknown
- 2001-01-23 PA PA20018510601A patent/PA8510601A1/es unknown
- 2001-01-23 AR ARP010100284A patent/AR029436A1/es unknown
- 2001-01-24 PE PE2001000076A patent/PE20011064A1/es not_active Application Discontinuation
- 2001-01-24 CO CO01005267A patent/CO5261537A1/es not_active Application Discontinuation
- 2001-01-24 HN HN2001000011A patent/HN2001000011A/es unknown
- 2001-01-24 TN TNTNSN01013A patent/TNSN01013A1/fr unknown
-
2002
- 2002-06-20 BG BG106851A patent/BG106851A/xx unknown
- 2002-06-25 IS IS6442A patent/IS6442A/is unknown
- 2002-07-22 MA MA26735A patent/MA26867A1/fr unknown
- 2002-07-23 ZA ZA200205880A patent/ZA200205880B/xx unknown
- 2002-07-24 NO NO20023526A patent/NO20023526L/no not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA27946A1 (fr) | Omega-carboxyaryldiphenyluree fluoro-substituee pour le traitement et la prevention de maladies et d'etats pathologiques. | |
| BE901224A (fr) | Nouveaux derives d'indole utiles comme medicaments et intermediaires et procedes pour leur preparation. | |
| MA27774A1 (fr) | Inhibiteurs de phosphatidylinositol 3-kinase | |
| MA30801B1 (fr) | Biaryl-ether-urees | |
| TNSN96172A1 (fr) | Composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| MA26697A1 (fr) | Composes nouveaux inhibiteurs de gsk-3 et compositions pharmaceutiques les contenant | |
| TNSN99106A1 (fr) | Derives d'isothiazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| TNSN99156A1 (fr) | Derives d'acide hydroxypipecolate-hydroxamique nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA28747B1 (fr) | Dérivés de pyridine | |
| TNSN99031A1 (fr) | Composes heterocycliques nouveaux inhibiteurs de romatases, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| MA25035A1 (fr) | Derives de 3-azabicyclo [3,1,0] hexane nouveaux, procede pour leur preparation et compositions les contenant | |
| MA28271A1 (fr) | Dérivés de benzènesulfonylamino-pyridine -2-yle et composés apparentés servant d'inhibiteurs de la 11-bêta- hydroxystéroïde-déshydrogénase de type 1(11-bêta-HSD-1)pour le traitement du diabète et de l'obésité | |
| MA26864A1 (fr) | Antagonistes du facteur de liberation de corticotrophine. | |
| TNSN98019A1 (fr) | Derives d'acide arylsulfonylaminohydroxamique, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| TNSN05250A1 (fr) | Pyrimidinones substituees | |
| TNSN01077A1 (fr) | Derives de tropane nouveaux, procede pour leur preparation et compositions les contenant | |
| TNSN98024A1 (fr) | 2-amino-6-(2-substitue-4-phenoxy)-substitue-pyridines, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| US4734421A (en) | Anti-inflammatory substituted 2-benzyl-mercapto-imidazole and pyrimidine derivatives compositions and method of use therefor | |
| TNSN01126A1 (fr) | Imidazoles substitues nouveaux, procede pour leur preparation et compositions les contenant | |
| TNSN01094A1 (fr) | Derives de 3-azabicyclo [3,1,0] hexane nouveaux, procede pour leur preparation et compositions les contenant | |
| TNSN03140A1 (fr) | Derives d'acides sulfoniques nouveaux. | |
| MA26867A1 (fr) | Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composés | |
| CN101084224A (zh) | 具有杀真菌活性的噻吩并－嘧啶化合物 | |
| JPH0539272A (ja) | ピリミジンジオン誘導体および除草剤 | |
| DE69628750T2 (de) | Neue antivirale, homocarbozklische nukleosidderivate von substituierten pyrimidindionen, verfahren zu ihrer herstellung und zusammensetzungen, die diese als aktiven bestandteil enthalten |