MA24273A1 - (4-arylthiazol-2yl) sulfonamides et leur utilisation - Google Patents

(4-arylthiazol-2yl) sulfonamides et leur utilisation

Info

Publication number: MA24273A1
Authority: MA; Morocco
Prior art keywords: arylthiazol; sulfonamides
Prior art date: 1996-07-19

Application number

MA24722A

Other languages

English (en)

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-19

Filing date

1997-07-17

Publication date

1998-04-01

1997-07-17 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1998-04-01 Publication of MA24273A1 publication Critical patent/MA24273A1/fr

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/50—Nitrogen atoms bound to hetero atoms
- C07D277/52—Nitrogen atoms bound to hetero atoms to sulfur atoms, e.g. sulfonamides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

MA24722A 1996-07-19 1997-07-17 (4-arylthiazol-2yl) sulfonamides et leur utilisation MA24273A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP96111661		1996-07-19

Publications (1)

Publication Number	Publication Date
MA24273A1 true MA24273A1 (fr)	1998-04-01

Family

ID=8223010

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24722A MA24273A1 (fr)	1996-07-19	1997-07-17	(4-arylthiazol-2yl) sulfonamides et leur utilisation

Country Status (23)

Country	Link
US (2)	US5877193A (fr)
EP (1)	EP0819681A3 (fr)
JP (1)	JP2991679B2 (fr)
KR (1)	KR100247672B1 (fr)
CN (1)	CN1176101A (fr)
AU (1)	AU725496B2 (fr)
BR (1)	BR9704023A (fr)
CA (1)	CA2210613A1 (fr)
CO (1)	CO4900053A1 (fr)
CZ (1)	CZ227397A3 (fr)
HR (1)	HRP970393A2 (fr)
HU (1)	HUP9701193A3 (fr)
IL (1)	IL121298A (fr)
MA (1)	MA24273A1 (fr)
MX (1)	MX9705385A (fr)
NO (1)	NO973338L (fr)
NZ (1)	NZ328331A (fr)
PE (1)	PE91298A1 (fr)
PL (1)	PL321203A1 (fr)
SG (1)	SG91796A1 (fr)
TR (1)	TR199700653A2 (fr)
YU (1)	YU30297A (fr)
ZA (1)	ZA976222B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9725138D0 (en) *	1997-11-27	1998-01-28	Pharmacia & Upjohn Spa	Thiophenesulfonamide compounds
GB9725141D0 (en) *	1997-11-27	1998-01-28	Pharmacia & Upjohn Spa	Benzenesulfonamide compounds
US6211185B1 (en) *	1999-05-05	2001-04-03	Veterinary Pharmacy Corporation	Concentrate comprising a sulfonamide in solution, a 2,4-diaminopyrimidine in stable suspension within said solution, and a suspending agent
SE0001899D0 (sv)	2000-05-22	2000-05-22	Pharmacia & Upjohn Ab	New compounds
CN1800176A (zh) *	2000-12-13	2006-07-12	惠氏	β淀粉样蛋白产生的杂环磺酰胺类抑制剂
ES2346961T3 (es)	2001-11-22	2010-10-22	Biovitrum Ab	Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa de tipo 1.
US6869970B2 (en)	2002-02-04	2005-03-22	Novartis Ag	Crystalline salt forms of valsartan
FR2849598B1 (fr) *	2003-01-07	2006-09-22	Merck Sante Sas	Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete, par augmentation du nombre de cellules des ilots de langerhans
FR2849599B1 (fr) *	2003-01-07	2006-12-29	Merck Sante Sas	Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete
JPWO2005054216A1 (ja) *	2003-12-01	2007-06-28	株式会社リバース・プロテオミクス研究所	新規抗癌剤「スルコキシン」
EP2054397B1 (fr) *	2006-08-16	2015-10-07	The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone	Inhibiteurs à petites molécules de kynurénine-3-monooxygénase
US8071631B2 (en) *	2006-08-16	2011-12-06	The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone	Small molecule inhibitors of kynurenine-3-monooxygenase
BRPI0905388A2 (pt) *	2008-01-15	2015-10-13	Siga Technologies Inc	"composição farmacêutica; compostos e métodos de tratamento de infecção por arenavirus"
WO2009124086A2 (fr) *	2008-04-04	2009-10-08	Siga Technologies, Inc.	Médicament antibactérien pour le traitement d’infections à staphylococcus aureus et d’autres bactéries gram positif
UA103319C2 (en) *	2008-05-06	2013-10-10	Глаксосмитклайн Ллк	Thiazole- and oxazole-benzene sulfonamide compounds
CN101602687A (zh) *	2008-06-13	2009-12-16	上海特化医药科技有限公司	6-硝基苯乙酮类化合物、其制备方法及用途
PH12017502049A1 (en) *	2011-08-30	2018-08-29	Chdi Foundation Inc	Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
CN102633687B (zh) *	2012-04-05	2016-06-08	天津瑞岭化工有限公司	一种对位取代烷基苯磺酰氯的制备方法和工艺
CN102633696A (zh) *	2012-04-05	2012-08-15	天津理工大学	一种两步合成制备对位取代烷基苯磺酰氯的方法和工艺
CN102633695A (zh) *	2012-04-05	2012-08-15	天津理工大学	一种4-异丙基苯磺酰氯的制备方法和工艺
CN102627589A (zh) *	2012-04-05	2012-08-08	天津理工大学	一种两步合成制备4-异丙基苯磺酰氯的方法和工艺
HK1208805A1 (zh) *	2012-09-21	2016-03-18	罗得岛医院	用於治療癌症的β-水解酶抑制劑
WO2017201468A1 (fr)	2016-05-20	2017-11-23	Xenon Pharmaceuticals Inc.	Composés benzènesulfonamides et leur utilisation en tant qu'agents thérapeutiques
JP7022751B2 (ja)	2016-12-09	2022-02-18	ゼノン・ファーマシューティカルズ・インコーポレイテッド	ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用
US10745392B2 (en)	2018-06-13	2020-08-18	Xenon Pharmaceuticals Inc.	Benzenesulfonamide compounds and their use as therapeutic agents
US10981905B2 (en)	2018-08-31	2021-04-20	Xenon Pharmaceuticals Inc.	Heteroaryl-substituted sulfonamide compounds and their use as therapeutic agents
EP3844158A1 (fr)	2018-08-31	2021-07-07	Xenon Pharmaceuticals Inc.	Composés de sulfonamide substitués par hétéroaryle et leur utilisation en tant qu'inhibiteurs de canaux sodiques
EP3846793B1 (fr) *	2018-09-07	2024-01-24	PIC Therapeutics, Inc.	Inhibiteurs d'eif4e et leurs utilisations
CN114516807B (zh) *	2022-02-24	2023-11-17	南京大学	一种含硝基多取代芳香二胺单体及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5591761A (en) *	1993-05-20	1997-01-07	Texas Biotechnology Corporation	Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
NZ247440A (en) *	1992-05-06	1995-04-27	Squibb & Sons Inc	Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof
CA2206315A1 (fr) *	1994-11-29	1996-06-06	Hisamitsu Pharmaceutical Co., Inc.	Utilisation de .beta.-carbolines halogenees en tant substances experimentales servant a provoquer des affections degeneratives
GB9702194D0 (en) *	1997-02-04	1997-03-26	Lilly Co Eli	Sulphonide derivatives

1997
- 1997-06-12 US US08/874,050 patent/US5877193A/en not_active Expired - Fee Related
- 1997-07-09 SG SG9702412A patent/SG91796A1/en unknown
- 1997-07-10 EP EP97111745A patent/EP0819681A3/fr not_active Ceased
- 1997-07-11 YU YU30297A patent/YU30297A/sh unknown
- 1997-07-11 PE PE1997000613A patent/PE91298A1/es not_active Application Discontinuation
- 1997-07-14 NZ NZ328331A patent/NZ328331A/xx unknown
- 1997-07-14 ZA ZA9706222A patent/ZA976222B/xx unknown
- 1997-07-14 IL IL12129897A patent/IL121298A/xx not_active IP Right Cessation
- 1997-07-14 HU HU9701193A patent/HUP9701193A3/hu unknown
- 1997-07-16 CA CA002210613A patent/CA2210613A1/fr not_active Abandoned
- 1997-07-16 MX MX9705385A patent/MX9705385A/es not_active Application Discontinuation
- 1997-07-16 JP JP9190990A patent/JP2991679B2/ja not_active Expired - Fee Related
- 1997-07-17 MA MA24722A patent/MA24273A1/fr unknown
- 1997-07-17 CO CO97040540A patent/CO4900053A1/es unknown
- 1997-07-17 TR TR97/00653A patent/TR199700653A2/xx unknown
- 1997-07-17 CZ CZ972273A patent/CZ227397A3/cs unknown
- 1997-07-18 CN CN97114715A patent/CN1176101A/zh active Pending
- 1997-07-18 AU AU28752/97A patent/AU725496B2/en not_active Ceased
- 1997-07-18 NO NO973338A patent/NO973338L/no not_active Application Discontinuation
- 1997-07-18 BR BR9704023A patent/BR9704023A/pt active Search and Examination
- 1997-07-18 HR HR96111661.3A patent/HRP970393A2/xx not_active Application Discontinuation
- 1997-07-18 PL PL97321203A patent/PL321203A1/xx unknown
- 1997-07-19 KR KR1019970033826A patent/KR100247672B1/ko not_active Expired - Fee Related
1998
- 1998-11-20 US US09/197,070 patent/US5958910A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUP9701193A2 (hu)	1999-02-01
NZ328331A (en)	1999-05-28
CZ227397A3 (cs)	1998-02-18
ZA976222B (en)	1998-01-19
PE91298A1 (es)	1998-12-31
AU725496B2 (en)	2000-10-12
JP2991679B2 (ja)	1999-12-20
EP0819681A2 (fr)	1998-01-21
CN1176101A (zh)	1998-03-18
EP0819681A3 (fr)	1998-02-04
PL321203A1 (en)	1998-02-02
AU2875297A (en)	1998-01-29
KR100247672B1 (ko)	2000-04-01
SG91796A1 (en)	2002-10-15
HUP9701193A3 (en)	2000-08-28
NO973338L (no)	1998-01-20
TR199700653A2 (xx)	1998-02-21
NO973338D0 (no)	1997-07-18
IL121298A (en)	2001-03-19
YU30297A (sh)	2000-10-30
IL121298A0 (en)	1998-01-04
JPH1067761A (ja)	1998-03-10
US5958910A (en)	1999-09-28
CO4900053A1 (es)	2000-03-27
HU9701193D0 (en)	1997-09-29
KR980008228A (ko)	1998-04-30
CA2210613A1 (fr)	1998-01-19
US5877193A (en)	1999-03-02
BR9704023A (pt)	1998-11-17
MX9705385A (es)	1998-04-30
HRP970393A2 (en)	1998-04-30

Publication	Publication Date	Title
MA24273A1 (fr)	1998-04-01	(4-arylthiazol-2yl) sulfonamides et leur utilisation
MA24237A1 (fr)	1997-12-31	Sulfonamides et leur utilisation.
NO984316D0 (no)	1998-09-17	Skjµreverkt°y
ID15921A (id)	1997-08-21	Peralatan pengeringan
NO983462D0 (no)	1998-07-28	Isoleringsverkt°y
DE69703584D1 (de)	2000-12-28	Kaskadierter anschluss von kommunizierenden geräte
ID17873A (id)	1998-02-05	Penghambat trombin baru
NO990552D0 (no)	1999-02-05	Innrettingsverkt°y
EP1012279A4 (fr)	2003-08-06	Genes de mitofusine et leur utilisation
DE69714146D1 (de)	2002-08-29	Polyether modifizierte Fluoralkylsiloxane
DE69724381D1 (de)	2003-10-02	Nichtreziproke Schaltungsanordnung
BR9708248A (pt)	1999-07-27	Benzotiofenos formulações contendo os mesmos e metódos
BR9707657A (pt)	1999-07-27	Benzotiofenos formulações contendo os mesmos e métodos
FI960994L (fi)	1997-09-05	Erotuslaite ja siinä olevia komponentteja
IS4998A (is)	1999-03-11	Flokkunarbúnaður
EP1241257A4 (fr)	2005-03-16	Polypeptides de type tachykinine et utilisation associee
EP1000925A4 (fr)	2001-08-08	Derives de triphenylmethane et leur utilisation
FR2757398B1 (fr)	2000-09-01	Formulation de bambuterol et son utilisation
FR2722198B1 (fr)	1996-10-04	1derives de silylmethyl-anilines, le2fabrication, et leur utilisation co
ID16791A (id)	1997-11-13	Peralatan pengering
DE69736101D1 (de)	2006-07-27	Y/C-Zweizeilen-Trennvorrichtung
DE69714188D1 (de)	2002-08-29	Y/C-Trennstufe
KR980000320U (ko)	1998-03-30	뺏지 부착용 핀
DE59703536D1 (de)	2001-06-21	Grenzwertschalter
KR970060791U (ko)	1997-12-10	게임용구