[go: up one dir, main page]

MA22885A1 - Nouveaux composes actifs. - Google Patents

Nouveaux composes actifs.

Info

Publication number
MA22885A1
MA22885A1 MA23178A MA23178A MA22885A1 MA 22885 A1 MA22885 A1 MA 22885A1 MA 23178 A MA23178 A MA 23178A MA 23178 A MA23178 A MA 23178A MA 22885 A1 MA22885 A1 MA 22885A1
Authority
MA
Morocco
Prior art keywords
carbohydrate
active compounds
immunogenic
peptide
new active
Prior art date
Application number
MA23178A
Other languages
English (en)
Inventor
Jondal Mikael
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9201338A external-priority patent/SE9201338D0/xx
Priority claimed from SE9202553A external-priority patent/SE9202553D0/xx
Priority claimed from SE9203897A external-priority patent/SE9203897D0/xx
Priority claimed from SE9301141A external-priority patent/SE9301141D0/xx
Application filed by Astra Ab filed Critical Astra Ab
Publication of MA22885A1 publication Critical patent/MA22885A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/605—MHC molecules or ligands thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA23178A 1992-04-28 1993-04-27 Nouveaux composes actifs. MA22885A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9201338A SE9201338D0 (sv) 1992-04-28 1992-04-28 New active compounds
SE9202553A SE9202553D0 (sv) 1992-09-07 1992-09-07 New active compounds ii
SE9203897A SE9203897D0 (sv) 1992-12-23 1992-12-23 New active compounds iii
SE9301141A SE9301141D0 (sv) 1993-04-06 1993-04-06 New active compounds iv

Publications (1)

Publication Number Publication Date
MA22885A1 true MA22885A1 (fr) 1993-12-31

Family

ID=27484749

Family Applications (1)

Application Number Title Priority Date Filing Date
MA23178A MA22885A1 (fr) 1992-04-28 1993-04-27 Nouveaux composes actifs.

Country Status (19)

Country Link
US (2) US5807559A (fr)
EP (1) EP0675733B1 (fr)
JP (1) JPH07506358A (fr)
CN (1) CN1096032A (fr)
AT (1) ATE197903T1 (fr)
AU (1) AU676679B2 (fr)
CA (1) CA2134097A1 (fr)
DE (1) DE69329735T2 (fr)
DK (1) DK0675733T3 (fr)
ES (1) ES2155070T3 (fr)
GR (1) GR3035501T3 (fr)
IL (1) IL105503A (fr)
IS (1) IS4010A (fr)
MA (1) MA22885A1 (fr)
MY (1) MY108864A (fr)
PT (1) PT675733E (fr)
SI (1) SI9300223A (fr)
TN (1) TNSN93045A1 (fr)
WO (1) WO1993021948A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083929A (en) * 1991-05-06 2000-07-04 The Biomembrane Institute Extended type 1 chain glycosphingolipids as tumor-associated antigens
DE4436164A1 (de) * 1994-10-10 1996-04-11 Hoechst Ag Neue Kohlenhydratkonjugate als Inhibitoren der Zelladhäsion
US6548643B1 (en) 1994-11-16 2003-04-15 Austin Research Institute Antigen carbohydrate compounds and their use in immunotherapy
US6841543B1 (en) 1996-01-31 2005-01-11 President And Fellows Of Harvard College Methods of inhibiting production of T helper type 2 cytokines in human immune cells
US6218363B1 (en) * 1996-08-28 2001-04-17 Thomas Jefferson University MHC peptides and methods of use
WO1998015286A1 (fr) * 1996-10-08 1998-04-16 La Jolla Institute For Allergy & Immunology Lymphocytes t a cytolyse specifique des glucides
US20070237785A1 (en) * 1997-03-27 2007-10-11 Institut Pasteur Multiple antigen glycopeptide carbohydrate, vaccine comprising the same and use thereof
DE69834808T2 (de) * 1997-03-27 2007-06-06 Institut Pasteur Multiple,kohlenhydrathaltige glycopeptid-antigene, daraus entwickelte impfstoffe sowie deren verwendung
US6660714B1 (en) 1997-04-16 2003-12-09 Sloan Kettering Institute For Cancer Research α-O-linked glycoconjugates, methods of preparation and uses thereof
US7550146B2 (en) * 1997-04-16 2009-06-23 Sloan-Kettering Institute For Cancer Research Glycopeptide conjugates and uses thereof
AUPO732997A0 (en) * 1997-06-12 1997-07-03 Csl Limited Ganglioside immunostimulating complexes and uses thereof
JP2002507577A (ja) * 1998-03-25 2002-03-12 スローン−ケッタリング インスティトュート フォア キャンサー リサーチ 三量体抗原性ｏ−結合複合糖ペプチド、その製造方法及びその使用
AU3456099A (en) 1998-03-31 1999-10-18 Geron Corporation Methods and compositions for eliciting an immune response to a telomerase antigen
US7402307B2 (en) 1998-03-31 2008-07-22 Geron Corporation Method for identifying and killing cancer cells
EP1073667A2 (fr) * 1998-04-28 2001-02-07 Galenica Pharmaceuticals, Inc. Conjugues d'antigene et de polysaccharide
US20030091546A1 (en) * 1998-11-12 2003-05-15 Barber Jack R. Methods of suppressing immune response by gene therapy
US7824687B2 (en) 1999-08-20 2010-11-02 Sloan-Kettering Institute For Cancer Research Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof
US7854934B2 (en) * 1999-08-20 2010-12-21 Sloan-Kettering Institute For Cancer Research Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
WO2001014395A2 (fr) 1999-08-20 2001-03-01 Sloan-Kettering Institute For Cancer Research Nouveaux glycoconjuges et acides glycoamino leurs intermediaires et leurs utilisations
DE10005275A1 (de) * 2000-02-07 2001-08-09 Bayer Ag Neuartige Glycokonjugate
US20030049253A1 (en) * 2001-08-08 2003-03-13 Li Frank Q. Polymeric conjugates for delivery of MHC-recognized epitopes via peptide vaccines
UA79952C2 (en) * 2001-12-10 2007-08-10 Kabulesh Mafatlal Khamar MYCOBACTERIUM w APPLICATIONS FOR CANCER TREATMENT
US7318926B2 (en) * 2003-02-06 2008-01-15 Tripep Ab Glycosylated specificity exchangers
WO2005077411A2 (fr) * 2004-02-10 2005-08-25 Innate Pharma Composition et procede pour le traitement de carcinome
US20060263415A1 (en) 2005-05-05 2006-11-23 Sensient Flavors Inc. Production of beta-glucans and mannans
ES2779992T3 (es) 2005-12-20 2020-08-21 Univ Duke Métodos y composiciones para suministrar agentes activos con propiedades farmacológicas potenciadas
EP2391635B1 (fr) 2009-01-28 2017-04-26 Epimmune Inc. Polypeptides de liaison de pan-dr et leurs utilisations
CA2794196A1 (fr) 2010-03-23 2011-09-29 Intrexon Corporation Vecteurs exprimant des proteines therapeutiques de maniere conditionnelle, cellules hotes comprenant les vecteurs, et utilisations associees
EP2500033A1 (fr) 2011-03-17 2012-09-19 Institut Pasteur Procédé pour la préparation de plusieurs conjugués de carbohydrate de glycopeptide d'antigène
KR102436439B1 (ko) 2011-06-28 2022-08-25 이노비오 파마수티컬즈, 인크. 최소 침습 피부 전기천공 장치
EP2606897A1 (fr) * 2011-12-22 2013-06-26 Laboratorios Del. Dr. Esteve, S.A. Procédés et compositions pour le traitement des maladies causées par les virus enveloppés
JP7210534B2 (ja) * 2017-07-12 2023-01-23 ザ・ボード・オブ・トラスティーズ・オブ・ザ・リーランド・スタンフォード・ジュニア・ユニバーシティ Ｈ３ｋ２７ｍ変異を有するがんの処置のための組成物および方法
WO2020163695A1 (fr) 2019-02-07 2020-08-13 Board Of Regents, The University Of Texas System Récepteurs d'antigènes chimériques de l'asperigillus et leurs utilisations
WO2020163682A1 (fr) 2019-02-07 2020-08-13 Board Of Regents, The University Of Texas System Récepteurs antigéniques chimériques du récepteur glucuronoxylomannane (gxm) et leurs utilisations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2004744B (en) * 1977-09-28 1982-05-26 Sanderson A R Immonulogical preparations
CA1335883C (fr) * 1986-07-08 1995-06-13 Bryan Michael Longenecker Stimulation de la reponse immunitaire cellulaire
WO1989006974A2 (fr) * 1988-02-01 1989-08-10 Praxis Biologics, Inc. Epitopes de cellules t a titre de molecules porteuses pour vaccins conjugues
EP0400077A4 (en) * 1988-02-12 1990-12-27 The Regents Of The University Of California Use of synthetic peptides to generate and manipulate cellular immunity
US5229289A (en) * 1988-03-11 1993-07-20 The Biomembrane Institute Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human and with synthetic carbohydrate-carrier conjugates
CA1337403C (fr) * 1988-03-28 1995-10-24 Biomembrane Institute (The) Methodes de production d'anticorps et induction de reponses immunitaires aux gangliosides associes aux tumeurs par immunisation avec des lactones de gangliosides
FI920131A7 (fi) * 1989-07-14 1992-01-13 American Cyanamid Co Sytokiini- ja hormonikantajia konjugaattirokotteita varten
CA2067124A1 (fr) * 1989-08-28 1991-03-01 Patricia L. Domen Vecteurs cationises pour la production d'immunogene
GB8924438D0 (en) * 1989-10-31 1989-12-20 Hoffmann La Roche Vaccine composition
IT1237764B (it) * 1989-11-10 1993-06-17 Eniricerche Spa Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.

Also Published As

Publication number Publication date
AU4274693A (en) 1993-11-29
EP0675733A1 (fr) 1995-10-11
SI9300223A (en) 1994-03-31
EP0675733B1 (fr) 2000-12-06
ES2155070T3 (es) 2001-05-01
PT675733E (pt) 2001-05-31
CN1096032A (zh) 1994-12-07
US5807559A (en) 1998-09-15
MY108864A (en) 1996-11-30
US6033669A (en) 2000-03-07
DE69329735D1 (de) 2001-01-11
CA2134097A1 (fr) 1993-11-11
ATE197903T1 (de) 2000-12-15
DE69329735T2 (de) 2001-08-02
IL105503A0 (en) 1993-08-18
GR3035501T3 (en) 2001-06-29
IL105503A (en) 1999-05-09
DK0675733T3 (da) 2001-05-07
IS4010A (is) 1993-10-29
JPH07506358A (ja) 1995-07-13
TNSN93045A1 (fr) 1994-03-17
WO1993021948A1 (fr) 1993-11-11
AU676679B2 (en) 1997-03-20

Similar Documents

Publication Publication Date Title
MA22885A1 (fr) Nouveaux composes actifs.
NO933028D0 (no) Peg-interferonkonjugater
ES2056215T3 (es) Composiciones de detergente.
EP1003526A4 (fr) N, o-carboxymethyl-chitosane a liaison covalente et ses applications
ATE88898T1 (de) Cd4-polypeptidderivate.
DE69531204D1 (de) Formulierungen fuer faktor ix
ATE296105T1 (de) Iminbildende polysaccharide, deren herstellung und verwendung als zusatzmittel und immunstimulierende mittel
NO304552B1 (no) Kompleksforbindelser, konjugater, farmas°ytiske preparater inneholdende slike og forbindelser
DK1137430T3 (da) Terapeutikum til undertrykkelse af snorkelyde
SE8206173L (sv) Nya plasminogenaktivatorderivat
BRPI9605663B8 (pt) Bis (resorcinil) triazinas.
IT1237764B (it) Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
ZA964822B (en) Antigenic group b streptococcus type ii and type iii polysaccharide- fragments having a 2,5-anhydro-d-mannose terminal structure and conjugate vaccine thereof
SE8504945L (sv) Farmaceutiska kompositioner innehallande antracyklinglykosider
ATE198834T1 (de) Konjugate bestehend aus polysaccharid und protein
TR199501654A3 (fr)
TW218847B (fr)
MX9708426A (es) Polipeptido hk2 de variante estable.
NZ506631A (en) Formulations for the stabilisation of PEG-interferon alpha conjugates during and after lyophilization
NZ235316A (en) Vaccine containing capsular polysaccharide conjugated to recombinant c protein of a group b streptococcus, production and use against b streptococcus infection
AR016427A1 (es) CONJUGADOS uTILES PARA EL TRATAMIENTO DE CÁNCER DE PRoSTATA, Y UNA COMPOSICIoN FARMACÉUTICA QUE LOS COMPRENDE.
IT8920898A0 (it) Uso di sucralfato gel umido per il trattamento di ulcere del derma e come veicolo di farmaci ad attivita' topica.
FI102462B1 (fi) Menetelmä nimesulidin syklodekstriinikompleksin valmistamiseksi
DK0822808T3 (da) Kompositmateriale med natriumstivelsesglycolat som bærermateriale og produkter deraf
ES2132891T3 (es) Procedimiento de preparacion de doxorrubicina.