Lam et al., 1998 - Google Patents
Application of “one-bead one-compound” combinatorial library methods in signal transduction researchLam et al., 1998
- Document ID
- 3133196169700679184
- Author
- Lam K
- Sroka T
- Chen M
- Zhao Y
- Lou Q
- Wu J
- Zhao Z
- Publication year
- Publication venue
- Life sciences
External Links
Snippet
Using a “split-synthesis” solid phase synthetic approach, bead libraries can be generated such that each bead displays only one chemical entity. This “one-bead one-compound” combinatorial library can then be assayed for specific biological properties using either a …
- 239000011324 bead 0 title abstract description 69
Classifications
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—For creating libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B30/00—Methods of screening libraries
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