[go: up one dir, main page]

O'Connor et al., 1975 - Google Patents

Effect of anoxic cardiac arrest and induced ventricular fibrillation on myocardial mitochondrial respiration and oxidative phosphorylation

O'Connor et al., 1975

View PDF
Document ID
2693123391088411674
Author
O'Connor F
Castillo-Olivares J
Gosalvez M
Figuera D
Publication year
Publication venue
Journal of Surgical Research

External Links

Snippet

Seventy-five healthy dogs were subjected to total cardiopulmonary bypass and divided in to three groups, according to the procedure employed to obtain cardiac arrest. In groups I and II, cardiac arrest was obtained by aortic cross clamping, and the perfusion was carried out at …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026Blood substitute; Oxygen transporting formulations; Plasma extender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons

Similar Documents

Publication Publication Date Title
Rosenkranz et al. Warm induction of cardioplegia with glutamate-enriched blood in coronary patients with cardiogenic shock who are dependent on inotropic drugs and intra-aortic balloon support: initial experience and operative strategy
US5405742A (en) Solutions for tissue preservation and bloodless surgery and methods using same
US5130230A (en) Blood substitute
EP0581883B1 (en) Blood substitutes and organ preservative solutions
Lower et al. Complete homograft replacement of the heart and both lungs
US4923442A (en) Blood substitute
Ellis et al. Relationship between atrioventricular arrhythmias and the concentration of K+ ion in cardioplegic solution
Gollan et al. Hypothermia of 1.5 C in dogs followed by survival
Ledingham et al. The St. Thomas’ Hospital cardioplegic solution: a comparison of the efficacy of two formulations
PT701455E (en) PLASMA SIMPLE SOLUTION
Gundry et al. Successful transplantation of hearts harvested 30 minutes after death from exsanguination
US5082831A (en) Total body washout solution and method of use
Ellis et al. Advantages of potassium cardioplegia and perfusion hypothermia in left ventricular hypertrophy
Chien et al. Two-day preservation of major organs with autoperfusion multiorgan preparation and hibernation induction trigger: A preliminary report
Kolobow et al. Massive pulmonary infarction during total cardiopulmonary bypass in unanesthetized spontaneously breathing lambs
Miller et al. Elective cardiac arrest: Its effect on myocardial structure and function
Grover et al. Does lower systemic temperature enhance cardioplegic myocardial protection?
Tucker et al. Questionable importance of high potassium concentrations in cardioplegic solutions
O'Connor et al. Effect of anoxic cardiac arrest and induced ventricular fibrillation on myocardial mitochondrial respiration and oxidative phosphorylation
Benesch et al. Enhanced oxygen unloading by an interdimerically crosslinked hemoglobin in an isolated perfused rabbit heart.
Gharagozloo et al. The effect of superoxide dismutase and catalase on the extended preservation of the ex vivo heart for transplantation
EP0664953A1 (en) Lung graft preservative composition and a method for viable preservation of lung grafts
Downing et al. Acute physiological changes following heart-lung allotransplantation in dogs
Scott et al. Limits of myocardial protection with potassium cardioplegia
Balibrea et al. Myocardial ultrastructural changes during extracorporeal circulation wtih anoxic cardiac arrest and its prevention by coronary perfusion. Experimental study.