[go: up one dir, main page]

Xu et al., 2007 - Google Patents

Electrochemical and optical detectors for capillary and chip separations

Xu et al., 2007

View PDF
Document ID
1923016493065824864
Author
Xu X
Li L
Weber S
Publication year
Publication venue
TrAC Trends in Analytical Chemistry

External Links

Snippet

In separations in capillaries or on chips, the most predominant detectors outside of the field of proteomics are electrochemical (EC) and optical. These detectors operate in the μM to pM range on nL peak volumes with ms time resolution. The driving forces for improvement are …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Micro-apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells

Similar Documents

Publication Publication Date Title
Fister et al. Counting single chromophore molecules for ultrasensitive analysis and separations on microchip devices
Uchiyama et al. Detection method for microchip separations
Fu et al. Laser-induced fluorescence detection system for microfluidic chips based on an orthogonal optical arrangement
Schulze et al. Deep UV laser-induced fluorescence detection of unlabeled drugs and proteins in microchip electrophoresis
Haab et al. Single-molecule detection of DNA separations in microfabricated capillary electrophoresis chips employing focused molecular streams
Wang et al. A miniaturized liquid core waveguide-capillary electrophoresis system with flow injection sample introduction and fluorometric detection using light-emitting diodes
Hooker et al. A transparent flow gating interface for the coupling of microcolumn LC with CZE in a comprehensive two-dimensional system
Schwarz et al. Recent developments in detection methods for microfabricated analytical devices
Shortreed et al. High-throughput single-molecule DNA screening based on electrophoresis
Huang et al. Chemiluminescence detection in capillary electrophoresis
Zhao et al. Integrated microfluidic system with chemiluminescence detection for single cell analysis after intracellular labeling
Baker et al. Recent advances in microfluidic detection systems
Pan et al. A low-cost palmtop high-speed capillary electrophoresis bioanalyzer with laser induced fluorescence detection
Lapos et al. Dual fluorescence and electrochemical detection on an electrophoresis microchip
Xu et al. Electrochemical and optical detectors for capillary and chip separations
Fang et al. A handheld laser-induced fluorescence detector for multiple applications
Fang et al. Sequential injection sample introduction microfluidic-chip based capillary electrophoresis system
Ryvolova et al. Combined contactless conductometric, photometric, and fluorimetric single point detector for capillary separation methods
US20090142853A1 (en) Microfluidic system and methods
Crabtree et al. Shah convolution fourier transform detection
JPH10507516A (en) Microfluidic operation method and apparatus for chemical analysis
Opekar et al. Rapid capillary zone electrophoresis along short separation pathways and its use in some hyphenated systems: a critical review
Linhardt et al. Ultra-high resolution separation comes of age
Tao et al. Optically gated capillary electrophoresis of o-phthalaldehyde/β-mercaptoethanol derivatives of amino acids for chemical monitoring
Wang et al. Rapid determination of creatinine in human urine by microchip electrophoresis with LED induced fluorescence detection