[go: up one dir, main page]

Akdemir et al., 2007 - Google Patents

p53 directs focused genomic responses in Drosophila

Akdemir et al., 2007

View PDF
Document ID
17263574050516471454
Author
Akdemir F
Christich A
Sogame N
Chapo J
Abrams J
Publication year
Publication venue
Oncogene

External Links

Snippet

Abstract p53 is a fundamental determinant of cancer susceptibility and other age-related pathologies. Similar to mammalian counterparts, Drosophila p53 integrates stress signals and elicits apoptotic responses that maintain genomic stability. To illuminate core-adaptive …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
    • C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity

Similar Documents

Publication Publication Date Title
Akdemir et al. p53 directs focused genomic responses in Drosophila
Doan et al. Recessive gene disruptions in autism spectrum disorder
Pickersgill et al. Characterization of the Drosophila melanogaster genome at the nuclear lamina
Myrick et al. Fragile X syndrome due to a missense mutation
Belyakin et al. Genomic analysis of Drosophila chromosome underreplication reveals a link between replication control and transcriptional territories
Larocque et al. Protection of p27Kip1 mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation
Silver et al. The exon junction complex component Magoh controls brain size by regulating neural stem cell division
Andrews et al. Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder
Harrison et al. Detection of prognostically relevant genetic abnormalities in childhood B‐cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin‐Frankfürt‐Münster study group
Post et al. Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction
Lacar et al. Nuclear RNA-seq of single neurons reveals molecular signatures of activation
Orvedahl et al. Image-based genome-wide siRNA screen identifies selective autophagy factors
Lai et al. Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning
Allebrandt et al. A KATP channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila
Neph et al. An expansive human regulatory lexicon encoded in transcription factor footprints
Kapfhamer et al. Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse
Tomlinson et al. Delta/Notch and Boss/Sevenless signals act combinatorially to specify the Drosophila R7 photoreceptor
Tayrac et al. Integrative genome‐wide analysis reveals a robust genomic glioblastoma signature associated with copy number driving changes in gene expression
Vigneau et al. An essential role for the DXPas34 tandem repeat and Tsix transcription in the counting process of X chromosome inactivation
Ogawa et al. Homeobox transcription factor Six7 governs expression of green opsin genes in zebrafish
Roppolo et al. Gene cluster lock after pheromone receptor gene choice
Oni et al. Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele
Niwa Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies
Levran et al. Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants
Lü et al. Genetic variations associated with six-white-point coat pigmentation in Diannan small-ear pigs