[go: up one dir, main page]

Margulies et al., 1992 - Google Patents

Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.

Margulies et al., 1992

Document ID
17002648166561344870
Author
Margulies I
Höyhtyä M
Evans C
Stracke M
Liotta L
Stetler-Stevenson W
Publication year
Publication venue
Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

External Links

Snippet

Accumulating experimental evidence has linked the overproduction of extracellular matrix- degrading metalloproteinases with tumor cell invasion. In the present study one member of the metalloproteinase family, type IV collagenase (M (r) 72,000 gelatinase), is shown to be …
Continue reading at aacrjournals.org (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/574—Immunoassay; Biospecific binding assay for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors

Similar Documents

Publication Publication Date Title
Margulies et al. Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.
AU2002211697B2 (en) Non-invasive enzyme screen for tissue remodelling-associated conditions
US5324634A (en) Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer
AU2002211697A1 (en) Non-invasive enzyme screen for tissue remodelling-associated conditions
Papadopoulou et al. Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa
JP2007504463A (en) Diagnostic markers for ovarian cancer
US5482848A (en) Matrix-degrading metalloproteinase
CA2252648C (en) Non-invasive enzyme screen for tissue remodelling-associated conditions
US6811995B1 (en) Non-invasive enzyme screen for cancer
Nabeshima et al. Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT) 1-MMP expressions are associated with malignant potential
Chu Prostate cancer-associated markers
US20040029200A1 (en) Method and kits for the detection of renal cell carcinoma in a biological fluid of a patient
Stetler-Stevenson Urinary Type IV Collagenase: Elevated Levels Are Associated with Bladder Transitional Cell Carcinoma
Di Carlo et al. Matrix metalloproteinase-2 and-9 in the urine of prostate cancer patients
Nakanishi et al. Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract
US6300088B1 (en) Method of detecting prostate specific antigen
Mareĉko et al. Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma
Swellam et al. Clinical implications of proteolytic activity imbalance in breast cancer diagnosis
Attallah et al. Combining nuclear matrix protein-52, collagen III, and matrix metalloproteinase-1 for more effective breast cancer early detection
EP1832876A2 (en) Non-invasive enzyme screen for tissue remodelling-associated conditions
Reddy et al. Isolation, purification and identification of matrilysin protein from canine mammary tumours and its quantification by indirect ELISA
WO1996024065A1 (en) Methods for the detection of pro-cathepsins and uses thereof
WO1996024065A9 (en) Methods for the detection of pro-cathepsins and uses thereof
Nielsen et al. TIMP-1 in Colorectal Cancer
JPWO1998029560A1 (en) Monoclonal antibody against collagenase 3 and immunoassay method using the same