[go: up one dir, main page]

Klugbauer et al., 1995 - Google Patents

Structure and functional expression of a new member of the tetrodotoxin‐sensitive voltage‐activated sodium channel family from human neuroendocrine cells.

Klugbauer et al., 1995

View PDF
Document ID
16903102412917057790
Author
Klugbauer N
Lacinova L
Flockerzi V
Hofmann F
Publication year
Publication venue
The EMBO journal

External Links

Snippet

A member of a new subclass of the voltage‐activated sodium channel genes has been cloned from the human medullary thyroid carcinoma (hMTC) cell line. The cDNA of hNE‐Na (human neuroendocrine sodium channel) encodes a 1977 amino acid protein which …
Continue reading at link.springer.com (PDF) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Similar Documents

Publication Publication Date Title
Klugbauer et al. Structure and functional expression of a new member of the tetrodotoxin‐sensitive voltage‐activated sodium channel family from human neuroendocrine cells.
US5492825A (en) Mammalian inward rectifier potassium channel cDNA, IRK1, corresponding vectors, and transformed cells
Grailhe et al. Human 5-HT5 receptors: the 5-HT5A receptor is functional but the 5-HT5B receptor was lost during mammalian evolution
Dietrich et al. Functional analysis of a voltage‐gated sodium channel and its splice variant from rat dorsal root ganglia
Burbidge et al. Molecular cloning, distribution and functional analysis of the NAV1. 6. Voltage-gated sodium channel from human brain
Nakajima et al. Cloning of cDNA and analysis of the gene for mouse angiotensin II type 2 receptor
Raymond et al. Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase
Fedida et al. Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current.
White et al. SkM2, a Na+ channel cDNA clone from denervated skeletal muscle, encodes a tetrodotoxin-insensitive Na+ channel.
Xia et al. Molecular basis for the inactivation of Ca2+-and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells
Gellens et al. Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel.
Stühmer et al. Potassium channels expressed from rat brain cDNA have delayed rectifier properties
Koschak et al. Cav1. 4α1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation
Ishii et al. Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases.
Frohnwieser et al. Modulation of the human cardiac sodium channel alpha‐subunit by cAMP‐dependent protein kinase and the responsible sequence domain.
Kubo et al. Primary structure and functional expression of a mouse inward rectifier potassium channel
McClatchey et al. The cloning and expression of a sodium channel β1-subunit cDNA from human brain
Hardie et al. Novel potassium channels encoded by the Shaker locus in Drosophila photoreceptors
Jegla et al. A novel subunit for shal K+ channels radically alters activation and inactivation
US5734021A (en) Inward rectifier, G-protein activated, mammalian potassium KGA channel polypepide
Obukhov et al. Direct activation of trpl cation channels by G alpha11 subunits.
Newman-Tancredi et al. High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells
Adams et al. Structural regions of the cardiac Ca channel α1C subunit involved in Ca-dependent inactivation
JP2004501627A (en) Mammalian 2P domain mechanosensitive K + channel, cloning and use thereof
MAROM et al. Mechanism and Modulation of Inactivation