[go: up one dir, main page]

Lin et al., 1999 - Google Patents

Structure-reactivity probes for active site shapes of cholesterol esterase by carbamate inhibitors

Lin et al., 1999

Document ID
15568190500160113081
Author
Lin G
Shieh C
Tsai Y
Hwang C
Lu C
Chen G
Publication year
Publication venue
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular Enzymology

External Links

Snippet

4, 4′-Biphenyl-di-N-butylcarbamate (1),(S)-1, 1′-bi-2-naphthyl-2, 2′-di-N-butylcarbamate (S-2),(S)-1, 1′-bi-2-naphthyl-2-N-butylcarbamate-2′-butyrate (S-3), 2, 2′-biphenyl-di-N- butylcarbamate (4), 2, 2′-biphenyl-2-N-octadecylcarbamate-2′-N-octylcarbamate (5), 2 …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving cholesterol

Similar Documents

Publication Publication Date Title
Terradas et al. Marked dependence of enzyme prochiral selectivity on the solvent
Hosie et al. p-Nitrophenyl and cholesteryl-N-alkyl carbamates as inhibitors of cholesterol esterase.
Li et al. Stereoselective detoxification of chiral sarin and soman analogues by phosphotriesterase
Zhang Kinetic and mechanistic characterization of a mammalian protein-tyrosine phosphatase, PTP1
Bartlett et al. Possible role for water dissociation in the slow binding of phosphorus-containing transition-state-analog inhibitors of thermolysin
Camps et al. Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer’s disease
Govardhan et al. Kinetics and mechanism of the serine. beta.-lactamase catalyzed hydrolysis of depsipeptides
Lin et al. Structure-reactivity probes for active site shapes of cholesterol esterase by carbamate inhibitors
Fidan et al. Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives
Lin et al. Structure− reactivity relationships for the inhibition mechanism at the second alkyl-chain-binding site of cholesterol esterase and lipase
Wei et al. Synthesis and biological evaluation of phosphorylated flavonoids as potent and selective inhibitors of cholesterol esterase
Sun et al. Targeting enteropeptidase with reversible covalent inhibitors to achieve metabolic benefits
Stadler et al. Inhibition of microbial lipases with stereoisomeric triradylglycerol analog phosphonates
Lin et al. Enantiomeric inhibitors of cholesterol esterase and acetylcholinesterase
Kovarik et al. Amino acid residues involved in the interaction of acetylcholinesterase and butyrylcholinesterase with the carbamates Ro 02-0683 and bambuterol, and with terbutaline
Jallouli et al. The galactolipase activity of Fusarium solani (phospho) lipase
Wang et al. Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A
Poyot et al. Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters
Vergara et al. Determination of the absolute configuration of the glucosinolate methyl sulfoxide group reveals a stereospecific biosynthesis of the side chain
Lin et al. Quantitative structure–activity relationships for the pre-steady-state inhibition of cholesterol esterase by 4-nitrophenyl-n-substituted carbamates
Apak et al. Interactions of the stereoisomers of α-hydroxytamoxifen with human hydroxysteroid sulfotransferase SULT2A1 and rat hydroxysteroid sulfotransferase STa
Hegde et al. Single-step synthesis of 4-nitrophenyl ferulate for spectrophotometric assay of feruloyl esterases
Masuoka et al. Xanthine oxidase inhibitory activity of alkyl gallates
Lin et al. Inhibition or activation of Pseudomonas species lipase by 1, 2-ethylene-di-N-alkylcarbamates in detergents
Van Oort et al. Kinetic behavior of porcine pancreatic phospholipase A2 on zwitterionic and negatively charged double-chain substrates