[go: up one dir, main page]

González-Vera et al., 2009 - Google Patents

Synthesis of red-shifted 8-hydroxyquinoline derivatives using click chemistry and their incorporation into phosphorylation chemosensors

González-Vera et al., 2009

View PDF
Document ID
1469098067001999204
Author
González-Vera J
Lukovic E
Imperiali B
Publication year
Publication venue
The Journal of organic chemistry

External Links

Snippet

Protein phosphorylation is a ubiquitous post-translational modification, and protein kinases, the enzymes that catalyze the phosphoryl transfer, are involved in nearly every aspect of normal, as well as aberrant, cell function. Here we describe the synthesis of novel, red …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/536—Immunoassay; Biospecific binding assay with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

Similar Documents

Publication Publication Date Title
González-Vera et al. Synthesis of red-shifted 8-hydroxyquinoline derivatives using click chemistry and their incorporation into phosphorylation chemosensors
Girouard et al. Synthesis and characterization of dimaleimide fluorogens designed for specific labeling of proteins
Guy et al. Convergent preparation and photophysical characterization of dimaleimide dansyl fluorogens: elucidation of the maleimide fluorescence quenching mechanism
Anai et al. Design of a hybrid biosensor for enhanced phosphopeptide recognition based on a phosphoprotein binding domain coupled with a fluorescent chemosensor
Hoogendoorn et al. Synthesis of pH-activatable red fluorescent BODIPY dyes with distinct functionalities
Kim et al. Fluorescent sensing of triphosphate nucleotides via anthracene derivatives
Wang et al. Structure‐based design of platinum (II) complexes as c‐myc oncogene down‐regulators and luminescent probes for g‐quadruplex DNA
Romero et al. A click-generated triazole tethered Ferrocene− Pyrene dyad for dual-mode recognition of the pyrophosphate anion
Salmon et al. Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII
Kim et al. Rhodamine triazole-based fluorescent probe for the detection of Pt2+
He et al. Structural simplification of bedaquiline: the discovery of 3‐(4‐(N, N‐Dimethylaminomethyl) phenyl) quinoline‐Derived antitubercular lead compounds
Mitra et al. Anticancer Activity of Hydrogen‐Bond‐Stabilized Half‐Sandwich RuII Complexes with Heterocycles
Bag et al. Installation/modulation of the emission response via click reaction
Hu et al. Development of a smart fluorescent sensor that specifically recognizes the c-MYC G-quadruplex
Maksimoska et al. Similar biological activities of two isostructural ruthenium and osmium complexes
Nano et al. A rhodium-cyanine fluorescent probe: Detection and signaling of mismatches in DNA
Pastor et al. Azino-fused benzimidazolium salts as DNA intercalating agents. 2.
Nanjunda et al. Halogenated pentamethine cyanine dyes exhibiting high fidelity for G-quadruplex DNA
Tremblay et al. A luminescent sensor for tyrosine phosphorylation
MacNevin et al. Ratiometric imaging using a single dye enables simultaneous visualization of Rac1 and Cdc42 activation
Ungati et al. Halogen‐Mediated Membrane Transport: An Efficient Strategy for the Enhancement of Cellular Uptake of Synthetic Molecules
Adhikari et al. Bis-amino acid derivatives of 1, 1′-ferrocenedicarboxylic acid: structural, electrochemical, and metal ion binding studies
Paulson et al. Design, synthesis, and characterization of a fluorescence polarization pan-BET bromodomain probe
Gray et al. Lighting up the thrombin-binding aptamer G-quadruplex with an internal cyanine-indole-quinolinium nucleobase surrogate. Direct fluorescent intensity readout for thrombin binding without topology switching
Kuruvilla et al. Novel bifunctional Acridine− Acridinium conjugates: Synthesis and study of their chromophore-selective electron-transfer and DNA-binding properties