Hitomi et al., 1995 - Google Patents
Sequence analysis of the hepatitis C virus (HCV) core gene suggests the core protein as an appropriate target for HCV vaccine strategiesHitomi et al., 1995
- Document ID
- 13837502179209188537
- Author
- Hitomi Y
- McDonnell W
- Killeen A
- Askari F
- Publication year
- Publication venue
- Journal of Viral Hepatitis
External Links
Snippet
Hepatitis C virus (HCV) is a major health problem with a prevalence of 1% in the United States population, and a significant percentage of infected patients progress to chronic liver disease and cirrhosis. Interferon therapy has demonstrated that the immune system can be …
- 241000711549 Hepacivirus C 0 title abstract description 91
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA Viruses positive-sense
- C12N2770/00011—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA Viruses positive-sense ssRNA Viruses positive-sense
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriphage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Farci et al. | Lack of protective immunity against reinfection with hepatitis C virus | |
| Ishii et al. | High titers of antibodies inhibiting the binding of envelope to human cells correlate with natural resolution of chronic hepatitis C | |
| Sugitani et al. | Sensitivity of serological assays to identify blood donors with hepatitis C viraemia | |
| Linnen et al. | Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent | |
| Botarelli et al. | T-lymphocyte response to hepatitis C virus in different clinical courses of infection | |
| AU746965B2 (en) | Cloned genomes of infectious hepatitis C viruses and uses thereof | |
| Harcourt et al. | Effect of HLA class II genotype on T helper lymphocyte responses and viral control in hepatitis C virus infection | |
| Kao et al. | Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis | |
| Naito et al. | Hepatitis C viral quasispecies in hepatitis C virus carriers with normal liver enzymes and patients with type C chronic liver disease | |
| US20080286756A1 (en) | Compositions and methods for diagnosing and treating severe acute respiratory syndrome (sars) | |
| JPH10295389A (en) | Method for culturing nanbv | |
| Birkenmeyer et al. | Isolation of a GB virus‐related genome from a chimpanzee | |
| Bukh et al. | Experimental infection of chimpanzees with hepatitis G virus and genetic analysis of the virus | |
| Iwata et al. | Interferon gamma production by peripheral blood lymphocytes to hepatitis C virus core protein in chronic hepatitis C infection | |
| CA2197569A1 (en) | Nucleotide and amino acid sequences of the envelope 1 and core genes of hepatitis c virus | |
| WO1994018217A1 (en) | Non-a, non-b, non-c, non-d, non-e hepatitis reagents and methods for their use | |
| Brown et al. | Prevalence of GBV‐C/HGV, a novel ‘hepatitis’ virus, in patients with aplastic anaemia | |
| Saito et al. | Sequence analysis of PePHD within HCV E2 region and correlation with resistance of interferon therapy in Japanese patients infected with HCV genotypes 2a and 2b | |
| Shao et al. | Sequence of hepatitis G virus genome isolated from a Japanese patient with non-A–E-hepatitis: amplification and cloning by long reverse transcription-PCR | |
| Tanaka et al. | Evolution of hepatitis G virus infection and antibody response to envelope protein in patients with transfusion‐associated non‐A, non‐B hepatitis | |
| EP0754193A1 (en) | Hepatitis c virus core peptide for stimulation of cytotoxic t lymphocytes and diagnosis of hcv exposure | |
| Troesch et al. | Characterization of humoral and cell-mediated immune responses directed against hepatitis C virus F protein in subjects co-infected with hepatitis C virus and HIV-1 | |
| EP1888752A2 (en) | Hepatitis c virus vaccine | |
| Hitomi et al. | Sequence analysis of the hepatitis C virus (HCV) core gene suggests the core protein as an appropriate target for HCV vaccine strategies | |
| US20080089903A1 (en) | Cd4+t-lymphocyte-specific hepatitis c virus epitopes |