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Van der Heijden et al., 1991 - Google Patents

Manipulation of intestinal immune responses against ovalbumin by cholera toxin and its B subunit in mice

Van der Heijden et al., 1991

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Document ID
13352455076703859442
Author
Van der Heijden P
Bianchi A
Dol M
Pals J
Stok W
Bokhout B
Publication year
Publication venue
Immunology

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Snippet

We studied the effect of mucosal presentation of ovalbumin (OVA) conjugated to cholera toxin (CT) or cholera toxin B subunit (CTB) on the intestinal immune responses against OVA. Mice were primed intraperitoneally (ip) with OVA in a water-in-oil emulsion and boosted …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
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    • A61K2039/55583—Polysaccharides
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    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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    • A61K2039/543—Mucosal route intranasal
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