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Cunha-Silva et al., 2020 - Google Patents

Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation

Cunha-Silva et al., 2020

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Document ID
1271291001079339769
Author
Cunha-Silva S
Osswald M
Goemann J
Barbosa J
Santos L
Resende P
Bange T
Ferrás C
Sunkel C
Conde C
Publication year
Publication venue
Journal of Cell Biology

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Snippet

The spindle assembly checkpoint (SAC) relies on the recruitment of Mad1-C-Mad2 to unattached kinetochores but also on its binding to Megator/Tpr at nuclear pore complexes (NPCs) during interphase. However, the molecular underpinnings controlling the …
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