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Louie et al., 2006 - Google Patents

Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases

Louie et al., 2006

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Document ID
11457482086540281054
Author
Louie G
Bowman M
Moffitt M
Baiga T
Moore B
Noel J
Publication year
Publication venue
Chemistry & biology

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Aromatic amino acid ammonia-lyases catalyze the deamination of L-His, L-Phe, and L-Tyr, yielding ammonia plus aryl acids bearing an α, β-unsaturated propenoic acid. We report crystallographic analyses of unliganded Rhodobacter sphaeroides tyrosine ammonia-lyase …
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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