[go: up one dir, main page]

Sebastião et al., 2019 - Google Patents

Bulk dynamic spray freeze-drying part 1: modeling of droplet cooling and phase change

Sebastião et al., 2019

View PDF
Document ID
10787731642531107106
Author
Sebastião I
Bhatnagar B
Tchessalov S
Ohtake S
Plitzko M
Luy B
Alexeenko A
Publication year
Publication venue
Journal of Pharmaceutical Sciences

External Links

Snippet

In spray freeze-drying (SFD), the solution is typically dispersed into a gaseous cold environment producing frozen microparticles that are subsequently dried via sublimation. This technology can potentially manufacture bulk lyophilized drugs at higher rates compared …
Continue reading at www.researchgate.net (PDF) (other versions)

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

Similar Documents

Publication Publication Date Title
Sebastião et al. Bulk dynamic spray freeze-drying part 1: modeling of droplet cooling and phase change
Sebastião et al. Bulk dynamic spray freeze-drying part 2: model-based parametric study for spray-freezing process characterization
Sadek et al. Drying of a single droplet to investigate process–structure–function relationships: a review
Schutyser et al. Single droplet drying for optimal spray drying of enzymes and probiotics
CA2574614C (en) Sterile freezing, drying, storing, assaying and filling process (sfd-saf process) (pellet freeze-drying process for parenteral biopharmaceuticals)
Chiou et al. The effect of temperature on the crystallinity of lactose powders produced by spray drying
US5727333A (en) Process for drying a material from solution
Sebastião et al. A kinetic model for spray-freezing of pharmaceuticals
Jiménez et al. Particles agglomeration in a conical fluidized bed in relation with air temperature profiles
US20080075777A1 (en) Apparatus and methods for preparing solid particles
Leuenberger et al. Spray freeze drying in a fluidized bed at normal and low pressure
Goshima et al. Impact of ice morphology on design space of pharmaceutical freeze-drying
Haque et al. Spray drying
Sebastião et al. Atmospheric spray freeze-drying: numerical modeling and comparison with experimental measurements
Rieck et al. Monte Carlo modeling of binder‐Less spray agglomeration in fluidized beds
Zhai et al. Measurement of lyophilisation primary drying rates by freeze-drying microscopy
Luy et al. Spray freeze drying
Turchiuli Fluidization in food powder production
Patel et al. Drying of aqueous lactose solutions in a single stream dryer
Rahman et al. Atmospheric freeze drying
Al-Hakim An investigation of spray-freezing and spray-freeze-dryings.
Tait et al. Numerical analysis of in-flight freezing droplets: Application to novel particle engineering technology
Steegmans et al. Spray freeze drying as a novel drying process for the formulation of probiotic powders containing Lacticaseibacillus rhamnosus GG
Huang et al. Phase and thermal diffusivity variation of saline water diagnosed by visual and temperature method during freezing process
Ruggiero Spray freeze-drying of pharmaceuticals