[go: up one dir, main page]

Nivet et al., 1991 - Google Patents

Synthesis and preliminary evaluation of perfluoroalkylacyl carnitines as surfactants for biomedical use

Nivet et al., 1991

Document ID
9921254592438304054
Author
Nivet J
Le Blanc M
Riess J
Publication year
Publication venue
European journal of medicinal chemistry

External Links

Snippet

A series of acyl carnitines, 4 of which bearing a terminal perfluoroalkyl fragment, was obtained from carnitine in one step in a high grade of purity in yields ranging from 44–81%. The F-alkyl derivatives display high solubilities in water, strong surface activity and a …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, -CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/937Dispersion or emulsion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms

Similar Documents

Publication Publication Date Title
JP3267292B2 (en) Amphiphilic fluorine derivatives with telomer structure; preparation and biomedical applications
TW396207B (en) Detergent composition
US5073362A (en) Dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides) and x-ray contrast media containing them
KR960016890A (en) Intravenous solution of staurosporin derivative
WO1998023580A1 (en) Polymerizable oligomesogenes
EP0105777A1 (en) Lipopeptides, their manufacture and use as emulsifiers
JP2002514190A (en) α-Branched fluoroalkylcarbonyl fluoride and its derivatives
Nivet et al. Synthesis and preliminary evaluation of perfluoroalkylacyl carnitines as surfactants for biomedical use
EP0485251A1 (en) Cosmetic, pharmaceutical or alimentary composition comprising a dispersion of lipid vesicles
KR100195291B1 (en) Nonionic vitamin E derivatives and a method for the preparation thereof, and polymeric amphiphilic vesicles made therefrom
Zarif et al. Synthesis of perfluoroalkylated xylitol ethers and esters: new surfactants for biomedical uses
JPH0322993A (en) Water-soluble L-tyrosine derivative and method for producing L-tyrosine derivative
KR19990082249A (en) Perfluoro (alkoxycycloalkane) carbonyl fluoride compositions and uses thereof
US5463117A (en) Process for the preparation of salts of 2-(4-isobutylphenyl)propionic acid
JPH0825927B2 (en) Oxygen transport agent
DE2153799A1 (en) Indoline derivatives
EP0311473A1 (en) Fluorinated derivate of amino acids, useful as tensioactive or cotensioactive agents, and preparations for biomedical use containing these derivatives
EP0257572B1 (en) Thyronin derivatives
US5621144A (en) Fluorinated compounds as oxygen transport agents
JP3860246B2 (en) Cationic Vitamin E Derivative, Process for Producing the Same, and Amphiphilic Polymer Formed Using the Same
Afzal et al. Syntheses of perfluoroalkyl N-polyethoxylated amides
Infante et al. Synthesis and properties of asymmetrical nonionic double chain surfactants from lysine
JPH03209346A (en) Fluorinated aliphatic group substituted ester and preparation thereof
EP1951381B1 (en) Novel lipophobic perfluoroalkyl polyamides, preparation thereof and use thereof
CH420191A (en) Process for the preparation of iodinated acylaminobenzoic acid amides and use of the same as a shading component in X-ray contrast media