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Thompson et al., 2004 - Google Patents

Regulation of the p300 HAT domain via a novel activation loop

Thompson et al., 2004

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Document ID
9816347601172795822
Author
Thompson P
Wang D
Wang L
Fulco M
Pediconi N
Zhang D
An W
Ge Q
Roeder R
Wong J
Levrero M
Sartorelli V
Cotter R
Cole P
Publication year
Publication venue
Nature structural & molecular biology

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Snippet

The transcriptional coactivator p300 is a histone acetyltransferase (HAT) whose function is critical for regulating gene expression in mammalian cells. However, the molecular events that regulate p300 HAT activity are poorly understood. We evaluated autoacetylation of the …
Continue reading at www.researchgate.net (PDF) (other versions)

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