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Wu et al., 2024 - Google Patents

Hyaluronic acid nanoparticles for targeted oral delivery of doxorubicin: Lymphatic transport and CD44 engagement

Wu et al., 2024

Document ID
8751771077420833325
Author
Wu Y
Li J
Liu L
Chu X
Zhong M
Li H
Zhao C
Fu H
Sun Y
Li Y
Publication year
Publication venue
International Journal of Biological Macromolecules

External Links

Snippet

The oral delivery of doxorubicin (DOX), an anti-cancer drug, encounters multiple hurdles such as limited gastrointestinal permeability, P-glycoprotein-mediated efflux, brief intestinal residence, and rapid degradation. This study introduced a novel approach utilizing …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
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