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Sealover et al., 2013 - Google Patents

Engineering Chinese Hamster Ovary (CHO) cells for producing recombinant proteins with simple glycoforms by zinc-finger nuclease (ZFN)—mediated gene knockout …

Sealover et al., 2013

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Document ID
7195361524510379854
Author
Sealover N
Davis A
Brooks J
George H
Kayser K
Lin N
Publication year
Publication venue
Journal of biotechnology

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While complex N-linked glycoforms are often desired in biotherapeutic protein production, proteins with simple, homogeneous glycan structure have implications for X-ray crystallography and for recombinant therapeutics targeted to the mannose receptor of …
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N9/10—Transferases (2.)
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