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Sotthivirat et al., 2013 - Google Patents

Development of amorphous solid dispersion formulations of a poorly water-soluble drug, MK-0364

Sotthivirat et al., 2013

Document ID
6350681776834074823
Author
Sotthivirat S
McKelvey C
Moser J
Rege B
Xu W
Zhang D
Publication year
Publication venue
International journal of pharmaceutics

External Links

Snippet

The goal of this study was to demonstrate that MK-0364 solid dispersions can be developed as a means to increase the solubility and bioavailability of a poorly water-soluble drug, MK- 0364. The potential solid dispersions would enable an oral solid dosage form as a …
Continue reading at www.sciencedirect.com (other versions)

Classifications

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    • A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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