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Hills et al., 2013 - Google Patents

BAIT: organizing genomes and mapping rearrangements in single cells

Hills et al., 2013

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Document ID
62531749791920296
Author
Hills M
O’Neill K
Falconer E
Brinkman R
Lansdorp P
Publication year
Publication venue
Genome medicine

External Links

Snippet

Strand-seq is a single-cell sequencing technique to finely map sister chromatid exchanges (SCEs) and other rearrangements. To analyze these data, we introduce BAIT, software which assigns templates and identifies and localizes SCEs. We demonstrate BAIT can refine …
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    • G06F19/22Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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    • G06F19/18Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for functional genomics or proteomics, e.g. genotype-phenotype associations, linkage disequilibrium, population genetics, binding site identification, mutagenesis, genotyping or genome annotation, protein-protein interactions or protein-nucleic acid interactions
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    • C12Q1/6802General aspects
    • C12Q1/6809Sequence identification involving differential detection

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