[go: up one dir, main page]

Hinman et al., 2017 - Google Patents

DNA linkers and diluents for ultrastable gold nanoparticle bioconjugates in multiplexed assay development

Hinman et al., 2017

View PDF
Document ID
4623404779244876383
Author
Hinman S
McKeating K
Cheng Q
Publication year
Publication venue
Analytical chemistry

External Links

Snippet

A novel bioconjugation strategy leading to ultrastable gold nanoparticles (AuNPs), utilizing DNA linkers and diluents in place of traditional self-assembled monolayers, is reported. The protective capacity of DNA confers straightforward biomolecular attachment and multistep …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

Similar Documents

Publication Publication Date Title
Zhang et al. Dual-aptamer-assisted ratiometric SERS biosensor for ultrasensitive and precise identification of breast cancer exosomes
Yang et al. Precise capture and direct quantification of tumor exosomes via a highly efficient dual-aptamer recognition-assisted ratiometric immobilization-free electrochemical strategy
Li et al. Fe3O4 nanozymes with aptamer-tuned catalysis for selective colorimetric analysis of ATP in blood
Geng et al. Noble metal nanoparticle biosensors: from fundamental studies toward point-of-care diagnostics
Cheng et al. Au@ Pd nanopopcorn and aptamer nanoflower assisted lateral flow strip for thermal detection of exosomes
Ye et al. An enzyme-free signal amplification technique for ultrasensitive colorimetric assay of disease biomarkers
Hinman et al. DNA linkers and diluents for ultrastable gold nanoparticle bioconjugates in multiplexed assay development
Guo et al. Oriented gold nanoparticle aggregation for colorimetric sensors with surprisingly high analytical figures of merit
Parolo et al. Design, preparation, and evaluation of a fixed-orientation antibody/gold-nanoparticle conjugate as an immunosensing label
Liang et al. Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate− protein interactions
Chen et al. Surface modification of gold nanoparticles with small molecules for biochemical analysis
Li et al. Organization of Inorganic Nanoparticles Using Biotin− Streptavidin Connectors
Li et al. Simultaneous imaging of Zn2+ and Cu2+ in living cells based on DNAzyme modified gold nanoparticle
Jung et al. Self-directed and self-oriented immobilization of antibody by protein G− DNA conjugate
Liu et al. Detection of membrane-binding proteins by surface plasmon resonance with an all-aqueous amplification scheme
Zhang et al. Size-dependent programming of the dynamic range of graphene oxide–DNA interaction-based ion sensors
Mao et al. Disposable nucleic acid biosensors based on gold nanoparticle probes and lateral flow strip
Kouassi et al. Magnetic and gold-coated magnetic nanoparticles as a DNA sensor
He et al. Aptamer recognition induced target-bridged strategy for proteins detection based on magnetic chitosan and silver/chitosan nanoparticles using surface-enhanced Raman spectroscopy
Yang et al. Polyelectrolyte-coated gold magnetic nanoparticles for immunoassay development: toward point of care diagnostics for syphilis screening
Algar et al. Adsorption and hybridization of oligonucleotides on mercaptoacetic acid-capped CdSe/ZnS quantum dots and quantum dot− oligonucleotide conjugates
Lin et al. Modified enzyme-linked immunosorbent assay strategy using graphene oxide sheets and gold nanoparticles functionalized with different antibody types
Rodriguez-Quijada et al. Physical properties of biomolecules at the nanomaterial interface
Chen et al. Impact of the Coverage of Aptamers on a Nanoparticle on the Binding Equilibrium and Kinetics between Aptamer and Protein
Gao et al. Microarray-based study of carbohydrate− protein binding by gold nanoparticle probes