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Bowyer, 1982 - Google Patents

Phencyclidine inhibition of the rate of development of amygdaloid kindled seizures

Bowyer, 1982

Document ID
4031894201446196947
Author
Bowyer J
Publication year
Publication venue
Experimental Neurology

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Snippet

Abstract Administration of (5, 10, 20 or 35 mg/kg, ip) phencyclidine (PCP) 15 min prior to each stimulation significantly reduced the rate of kindling induced by daily electrical stimulation of the amygdala in the rat. All four doses significantly reduced the rate of kindling …
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A—HUMAN NECESSITIES
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