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  • Washedupcynic@lemmy.ca
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    3 days ago

    He wasn’t going through opioid withdraw, he was going through alcohol withdrawl, which can be just as dangerous cold turkey quitting. Alcohol has non specific effects in the brain, inhibiting excitatory neurotransmission by acting on NMDA receptors, and accentuating inhibitory transmission by acting on GABA receptors. Stopping cold turkey causes hallucinations and seizures due to the jump in excitatory neurotransmission. Keppra is an anticonvulsant that blocks high voltage gated calcium channels, which I sort of feel is an inappropriate medication on it’s own, might have been better to pair it with a low does of memantine/ketamine or a benzodiazapine class drug.