JA Ōmura Award winners

The Journal of Antibiotics Ōmura Award for Excellence is given annually to an original research article and a review article selected from the previous three volumes of the journal. Winners are selected by the Editorial Board.

 

 

 

 

2024 JA Ōmura Award Winners

Announcement Article

Original Research Article:

Cycloimidamicins, Novel natural lead compounds for translation inhibition in Pseudomonas aeruginosa

Yoshimasa Ishizaki, Maya Umekita, Rie Arisaka, Masaki Hatano, Tomoyuki Kimura, Yumiko Kubota, Yuko Shibuya, Chigusa Hayashi, Ryuichi Sawa, and Masayuki Igarashi

Review Article:

Antibiotics in the clinical pipeline as of December 2022

Mark S. Butler, Ian R. Henderson, Robert J. Capon, and Mark A. T. Blaskovich

 

2023 JA Ōmura Award Winners

Announcement Article

Original Research Article:

Wychimicins, a new class of spirotetronate polyketides from Actinocrispum wychmicini MI503-A4

Tomoyuki Kimura, Maya Umekita, Masaki Hatano, Chigusa Hayashi, Ryuichi Sawa, and Masayuki Igarashi

Review Article:

Highlights of marine natural products having parallel scaffolds found from marine-derived bacteria, sponges, and tunicates

Erin P. McCauley, Ivett C. Piña, Alyssa D. Thompson, Kashif Bashir, Miriam Weinberg, Shannon L. Kurz, and Phillip Crews

 

2022 JA Ōmura Award Winners

Announcement Article

Original Research Article:

Azithromycin, a 15-membered macrolide antibiotic, inhibits influenza A(H1N1)pdm09 virus infection by interfering with virus internalization process

Dat Huu Tran, Ryuichi Sugamata, Tomoyasu Hirose, Shoichi Suzuki, Yoshihiko Noguchi, Akihiro Sugawara, Fuyu Ito, Tomoko Yamamoto, Shoji Kawachi, Kiyoko S. Akagawa, Satoshi Ōmura, Toshiaki Sunazuka, Naoki Ito, Masakazu Mimaki & Kazuo Suzuki

Review Article:

Splicing modulators: on the way from nature to clinic

Tilman Schneider-Poetsch, Jagat Krishna Chhipi-Shrestha & Minoru Yoshida

 

2021 JA Ōmura Award Winners

Announcement Article

Original Research Article:

Discovery of “heat shock metabolites” produced by thermotolerant actinomycetes in high-temperature culture

Shun Saito, Wataru Kato, Hiroaki Ikeda, Yohei Katsuyama, Yasuo Ohnishi & Masaya Imoto

Review Article:

Role of symbiosis in the discovery of novel antibiotics

Vedanjali Gogineni, Xiaoyan Chen, George Hanna, Dian Mayasari & Mark T. Hamann

 

2020 JA Ōmura Award Winners

Announcement Article

Original Research Article:

Enhanced dereplication of fungal cultures via use of mass defect filtering

Noemi D Paguigan, Tamam El-Elimat, Diana Kao, Huzefa A Raja, Cedric J Pearce & Nicholas H Oberlies

Review Article:

Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations

Andy Crump

 

2019 JA Ōmura Award Winners

Announcement Article

Original Research Articles:

Discovery of a new antifungal agent ASP2397 using a silkworm model of Aspergillus fumigatus infection

Ikuko Nakamura, Ryuichi Kanasaki, Koji Yoshikawa, Shigetada Furukawa, Akihiko Fujie, Hiroshi Hamamoto & Kazuhisa Sekimizu

ASP2397: a novel antifungal agent produced by Acremonium persicinum MF-347833

Ikuko Nakamura, Seiji Yoshimura, Teruhisa Masaki, Shigehiro Takase, Keisuke Ohsumi, Michizane Hashimoto, Shigetada Furukawa & Akihiko Fujie

Review Article:

Bacterial proteases, untapped antimicrobial drug targets

Elizabeth Culp & Gerard D Wright

 

2018 JA Ōmura Award Winners

Announcement Article

Original Research Article:

Novel terpenes generated by heterologous expression of bacterial terpene synthase genes in an engineered Streptomyces host

Yuuki Yamada, Shiho Arima, Tohru Nagamitsu, Kohei Johmoto, Hidehiro Uekusa, Tadashi Eguchi, Kazuo Shin-ya, David E Cane & Haruo Ikeda

Review Article:

The antibiotic resistance crisis, with a focus on the United States

Evan Martens & Arnold L Demain

 

2017 JA Ōmura Award Winners

Announcement Article

Original Research Article:

Application of bacterial cytological profiling to crude natural product extracts reveals the antibacterial arsenal of Bacillus subtilis

Poochit Nonejuie, Rachelle M Trial, Gerald L Newton, Anne Lamsa, Varahenage Ranmali Perera, Julieta Aguilar, Wei-Ting Liu, Pieter C Dorrestein, Joe Pogliano & Kit Pogliano

Review Article:

Glycopeptide antibiotics: Back to the future

Mark S Butler, Karl A Hansford, Mark A T Blaskovich, Reena Halai & Matthew A Cooper

 

2016 JA Medal Winners

Announcement Article

Original Research Article:

Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitors

Shajila Siricilla, Katsuhiko Mitachi, Bajoie Wan, Scott G Franzblau & Michio Kurosu

Review Article:

Glycopeptide antibiotic biosynthesis

Grace Yim, Maulik N Thaker, Kalinka Koteva & Gerard Wright

 

2015 JA Medal Winners

Announcement Article

Original Research Article:

MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus

Wei-Ting Liu, Anne Lamsa, Weng Ruh Wong, Paul D Boudreau, Roland Kersten, Yao Peng, Wilna J Moree, Brendan M Duggan, Bradley S Moore, William H Gerwick, Roger G Linington, Kit Pogliano & Pieter C Dorrestein

Review Article:

Prospects for new antibiotics: a molecule-centered perspective

Christopher T Walsh & Timothy A Wencewicz

 

2014 JA Medal Winners

Announcement Article

Original Research Article:

Occurrence, distribution, dereplication and efficient discovery of thiazolyl peptides by sensitive-resistant pair screening

Sheo B Singh, Chaowei Zhang, Deborah L Zink, Kithsiri Herath, John Ondeyka, Prakash Masurekar, Hiranthi Jayasuriya, Michael A Goetz, Jose Rubén Tormo, Francisca Vicente, Jesús Martín, Ignacio González & Olga Genilloud

Review Article:

Towards a new science of secondary metabolism

Arryn Craney, Salman Ahmed & Justin Nodwell

 

2013 JA Medal Winners

Announcement Article

Original Research Article:

Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions

Dylan C Alexander, Jessica Rock, Jian-Qiao Gu, Carmela Mascio, Min Chu, Paul Brian & Richard H Baltz

Review Article:

Antibiotics in the Clinical Pipeline in 2011

Mark S Butler & Matthew A Cooper

 

2012 JA Medal Winners

Announcement Article

Original Research Article:

Decalpenic acid, a novel small molecule from Penicillium verruculosum CR37010, induces early osteoblastic markers in pluripotent mesenchymal cells

Shuichi Sakamoto, Fukiko Kojima, Masayuki Igarashi, Ryuichi Sawa, Maya Umekita, Yumiko Kubota, Koichi Nakae, Shoichi Yamaguchi, Hayamitsu Adachi, Yoshio Nishimura & Yuzuru Akamatsu