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IMDbPro

Common Side Effects

  • TV Series
  • 2024–
  • TV-MA
IMDb RATING
8.5/10
13K
YOUR RATING
POPULARITY
535
46
Dave King and Emily Pendergast in Common Side Effects (2024)
Watch Trailer - Season 1
Play trailer1:31
4 Videos
7 Photos
Adult AnimationConspiracy ThrillerDark ComedyHand-Drawn AnimationAnimationComedyDramaThriller

Follows former high school lab mates Marshall and Frances as they unravel a conspiracy involving big pharma and the government to suppress knowledge of a rare fungus secret that may contain ... Read allFollows former high school lab mates Marshall and Frances as they unravel a conspiracy involving big pharma and the government to suppress knowledge of a rare fungus secret that may contain the solution to cure all world's diseases.Follows former high school lab mates Marshall and Frances as they unravel a conspiracy involving big pharma and the government to suppress knowledge of a rare fungus secret that may contain the solution to cure all world's diseases.

  • Creators
    • Joseph Bennett
    • Steve Hely
  • Stars
    • Dave King
    • Emily Pendergast
    • Mike Judge
  • See production info at IMDbPro
  • IMDb RATING
    8.5/10
    13K
    YOUR RATING
    POPULARITY
    535
    46
    • Creators
      • Joseph Bennett
      • Steve Hely
    • Stars
      • Dave King
      • Emily Pendergast
      • Mike Judge
    • 75User reviews
    • 11Critic reviews
  • See production info at IMDbPro
    • Nominated for 1 Primetime Emmy
      • 3 nominations total

    Episodes11

    Browse episodes
    TopTop-rated2025

    Videos4

    Trailer - Season 1
    Trailer 1:31
    Trailer - Season 1
    Common Side Effects: Season 1
    Trailer 0:38
    Common Side Effects: Season 1
    Common Side Effects: Season 1
    Trailer 0:38
    Common Side Effects: Season 1
    Common Side Effects: Trailer 2
    Trailer 1:10
    Common Side Effects: Trailer 2
    Common Side Effects
    Trailer 1:31
    Common Side Effects

    Photos6

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    Top cast20

    Edit
    Dave King
    Dave King
    • Marshall Cuso
    • 2024–2025
    Emily Pendergast
    Emily Pendergast
    • Frances Applewhite
    • 2024–2025
    Mike Judge
    Mike Judge
    • Rick Kruger…
    • 2024–2025
    Martha Kelly
    Martha Kelly
    • Agent Harrington
    • 2024–2025
    Joseph Lee Anderson
    Joseph Lee Anderson
    • Agent Copano
    • 2024–2025
    Sue Rose
    • Hildy
    • 2025
    Shannon Woodward
    Shannon Woodward
    • Amelia…
    • 2024–2025
    Ben Feldman
    Ben Feldman
    • Nick…
    • 2024–2025
    Sydney Tamiia Poitier
    Sydney Tamiia Poitier
    • Cecily
    • 2025
    Danny Huston
    Danny Huston
    • Jonas Backstein
    • 2025
    Shalita Grant
    Shalita Grant
    • Kelly…
    • 2024–2025
    Steve Hely
    • Rusty
    • 2025
    Christine Ko
    Christine Ko
    • Kiki
    • 2025
    Alan Resnick
    Alan Resnick
    • Zane
    • 2025
    Jon Foor
    • Hoang
    • 2025
    Bob Stephenson
    Bob Stephenson
    • Connor…
    • 2025
    Lin Shaye
    Lin Shaye
    • Sonia
    • 2025
    Timothy Simons
    Timothy Simons
    • DEA Dispatcher…
    • 2025
    • Creators
      • Joseph Bennett
      • Steve Hely
    • All cast & crew
    • Production, box office & more at IMDbPro

    User reviews75

    8.513.4K
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    Summary

    Reviewers say 'Common Side Effects' is a groundbreaking animated series praised for its dark humor, sharp social commentary, and surreal visuals. The show critiques corporate greed and the pharmaceutical industry, provoking deep reflection. Unique animation style and exceptional voice acting are highlighted. However, some note pacing issues and a meandering story. Mixed opinions exist on animation quality, with some finding it crude. Despite critiques, most reviewers highly recommend the show for its originality and engaging content.
    AI-generated from the text of user reviews

    Featured reviews

    10wfgle

    Unlike anything before

    Common Side Effects feels like the next great high-concept adult animation. The first two episodes blend dark humor, sharp social commentary, and surreal visuals in a way that's thought-provoking and inspiring. The story hits on corporate greed, the pharma industry, and human curiosity-but does so in a way that's weird and unpredictable. The writing is clever, the animation is unique, and the voice acting is spot-on. It's the kind of show that sticks with you after watching, leaving you excited for what's next. If the rest of the season keeps this pace, it'll be one of Adult Swim's GOAT shows for sure.
    10c-figueroa10

    Refreshing.

    Had no idea about this show so went in totally blind. Seeing Mike Judge attached as the producer gave me high hopes and it does not disappoint. The animation style is really different and took a couple episodes to get used to but I love it now and it suits the tone of the show perfectly. The voice acting is great and the storyline of a guy being hunted down by big pharma for finding a cure all mushroom in the wild is refreshing and not something that has ever been done, especially when it comes to animation. I really hope that Adult Swim continues with this series and stick with the same writers etc. Because they really got a good one here. I give season 1 a solid 10/10 me and my partner both love it, it's really entertaining and the 22-25 minute episode run-times are perfect. Give it a watch, I'd definitely recommend it if you enjoy mature animation. It's also pretty funny at times and the intro is awesome.
    8vishnuthulasidharan

    I'm in and staying

    Just when I thought scavenger's reign was one of the best animated shows I've seen this gem comes along and puts me on a new road of awesomeness, I'm truly excited to have experienced this show unexpectedly..I don't know what yo say I loved every single episode like I was a kid Infront of TV diving into his favourite cartoon show.yes..this show actually made me feel that, and for that I'm giving it a solid 8 score, I just humbly hope the creators continue to be respectful towards the plot as well as every viewer who loved watching it, no need to rush anything keep it going as it is and develop characters and branch out to new stories that are interesting and suspenseful like previous episodes. I've been fan from the begining and I hope to continue on that path..best of luck to the team behind this wonderful show and thank you.
    10calahao

    Lots of potential

    This series strikes just the right nerve with me. It portrays two people with an all cure drug fighting against Big Pharma, which in the precise moment this was released it is extremely topical and warranted.

    The animation is alright, but it really spikes up during psychadelic scenes, in some ways reminescent of Scavengers Reign. The character designs are a bit of a mixed feeling: most characters have rather large heads that make them look like adult babies. Ah well.

    The humor is usually pretty subdued, which is great as it allows for comedic moments to hit harder. The characters are just the right mixture of likeable and self-centered.

    A strong recommendation.
    10mryan-55579

    Shockingly Good

    This show is outstanding. The fact that an adult swim animated series is this well written and executed is fairly surprising, The last show they had that was at this level was The Venture Bros, and this show leans significantly further towards the drama side of the aisle. It's highly impressive how good the storytelling and serialization for a late night animated series. The animation style is offbeat yet visually appealing. The voice acting is top notch and well suited for each character in the series. I cannot wait for new episodes, and I'm fairly confident in their ability to wrap up the season. Go watch this now!!

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    Storyline

    Edit

    Did you know

    Edit
    • Trivia
      The pilot was screened at Annecy Festival 2024 and at San Diego Comic Con 2024 (as part of Adult Swim's annual festival event).
    • Connections
      Featured in WatchMojo: Top 10 TV Shows of 2025 So Far (2025)

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    Details

    Edit
    • Release date
      • February 2, 2025 (United States)
    • Country of origin
      • United States
    • Language
      • English
    • Also known as
      • Efectos secundarios
    • Production companies
      • Bandera Entertainment
      • Green Street Pictures
      • Hely Enterprises
    • See more company credits at IMDbPro

    Tech specs

    Edit
    • Color
      • Color

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    Dave King and Emily Pendergast in Common Side Effects (2024)
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