When a massive explosion at a top-secret prison allows notorious serial killer Richard Harris to escape, disgraced FBI agent Bex Henderson is called back into action to hunt him down before he kills again.
Clayton Jessup, a deranged killer who targets happy families, is on the loose and looking to kill again, sending the team on a manhunt to stop him. Bex learns who she can and can't trust.
In rural Montana, the team hunts down Brenda Lowe, a brutal serial killer obsessed with wolves. Bex and the team must track Lowe through the wilderness, all while dealing with local Rangers out for their own form of vigilante justice.
Dr. Ezekiel Malak, a hospital psychiatrist turned deranged killer, is prowling for new victims in Chicago, so Bex and the team work to find a method to his madness in a desperate bid to get ahead of him.
When Bex and the team race to stop Roy Barber, known as the Couple Killer, before he strikes again, they uncover a chilling scheme that puts Roy's crimes in an entirely new light.
Arlo Brandt, a hoarder-turned-serial killer, emerges from the Pit with newly found purpose. As Arlo hunts for innocent victims, Bex and the team must get inside a deranged mind.
Bex and the team race to catch Mark Marsden, known as the Widower, a handsome and charming serial killer who murdered three of his wives in cold blood. Everything changes when Mark decides to take a new bride.
The student becomes the master, when an escaped serial killer from the Pit decides to adopt another inmate's style of killing as a way of paying homage to them.
Bex and the team track the brilliant and beguiling Jenna Wells, the notorious Killer Chemist, whose therapy in the Pit has made her even more dangerous and deranged.
