The use of Maquette Monsters have been re-approved. Maquette Monsters created from data collected from past monsters, can fight alongside humans as allies.
The C-Pin 929 emergency rations Alien Fanton dropped on Earth came into contact with the atmosphere due to High-Dimensional Predator Bogal and begins to grow infinitely.
Just as Tsurugi is about to die, Mother of Ultra appears. Meanwhile back on Earth, Dinozaur who the GUYS once defeated has been resurrected as the twin-headed Dinozaur Reverse.
Adjutant Toriyama loses a dangerous research item that was scheduled for disposal. The Meteor named Grote's Cell can enter hollow objects and move them like they were alive.
A duel between aliens takes place on Oshima's Comet. The intense fighting causes the comet to enter a trajectory headed for Earth, and GUYS prepare to intercept.
GUYS struggles with Monster Salamandra who regenerates no matter how many times it's defeated. Ultraman Hikari appears, but is fatigued from countless battles.
Now that Ultraman Hikari has returned to the Land of Light, Mebius is the only Ultraman left on Earth. Mirai struggles with the heavy responsibility of being an Ultraman.
GUYS begin the Hamelin Project experiment, which uses special sound waves to guide monsters. However, the effects of these sound waves cause two large monsters to emerge.
A distress signal from the spacecraft Arandas is received from the Ultra Zone in space. Mirai insists GUYS go investigate, believing there might still be survivors from the lost spaceship.
Mirai modeled his human body after Hiroto, the son of the Arandas' captain. Upon meeting Mirai, the spitting image of his son, Captain Ban recalls the tragic day.
The police ask Marina to help investigate a case of mass disappearances that occur with ocean sounds. Marina works with Detective Tori who she finds strangely familiar.
The influential other-dimensional physicist Professor Fujisawa returns to Japan. Yapool uses Terrible-Monster Doragory to secretly take control of Professor Fujisawa.
Just when GUYS was going to deploy a weapon to fight against Super Beast from coming through Yapool's inter-dimensional gate, Captain Sakomizu is injured in an attack.
One day when the base is filled with rumors of the emergence of a red ghost, Konomi reunites with a young man named Suzaki who gave her courage when she was a child.
As danger closes in on Earth, young Mebius receives orders to return to the Land of Light. Despite his anguish, Mirai says goodbye to each of his friends.
The GUYS SPACY defense line is broken, and UFOs appear all around the world. It is discovered that this new race of flying saucer aliens have orders to exterminate Mebius.
Teppei falls head over heels for a girl named Misa, but she is possessed by Femigon. Femigon is said to create panic and engulf areas of panic in flames.
Arigera with its incredible flight abilities just invaded Earth. GUYS and Mebius struggle against this foe, but are saved by Isana, an elite member of GUYS Ocean.
Sayuri Hinode, a cafeteria worker on the GUYS Phoenix Nest base, dies in a traffic accident. Sayuri had unfinished business with her children and is resurrected by "Alien Serpent."
Minus Energy causing the appearance of monsters are happening at the same time as closing of a middle school. The former students have a reunion to see their inspiration Ultraman 80 again.
Deathrem holds the Phoenix Nest and GUYS hostage to force Ultraman Mebius into a confrontation. Save his friends or defend the people of Earth. Ultraman Jack helps him make the right choice.
