On Wallach IX, young Valya Harkonnen promises Mother Superior Raquella that she'll protect the Sisterhood by putting one of their own on the Imperial Throne. Thirty years later, Valya faces a threat to her long-awaited plan.
Following two Harkonnen sisters as they combat forces that threaten the future of humankind and establish the fabled sect that will become known as the Bene Gesserit.
Following a tragedy, young Tula worries about being accepted despite her family name, while a skeptical Valya struggles with the decision to take the vow of Sisterhood.
Tula tries to understand the origins of the nightmare that affects all acolytes of the sisterhood; Valya plans to rehabilitate House Harkonnen before the great meeting of the Landsraad.
A Sister with imperial ties arrives on Salusa Secundus as the Corrinos appoint a new Bashar. Desmond hunts insurgents following a tip, while Tula conceals a covert project.
