Donna Yamamoto nasceu em agosto de 1962 em Vancouver, British Columbia, Canadá. É atriz, conhecida pelo seu trabalho em 50% (2011), 2012 (2009) e Deadpool (2016).
In 2016 was named "International Women's Day Honoree" by the UBCP (Union of British Columbia Performers) Women's Committee for her history of giving back to the union, the industry, and causes of social justice.