Kamal Haasan, whenever he speaks about cancer, he always mentions about the Malayalam actor Sathyan, who suffered blood cancer. Sathyan used to clean up himself from the disease between the shots. He would rush to the hospital, take his treatment and come back for the shot. A similar sequence can be found in this movie when Margadarshi finds blood oozing out from Manoranjan's nose. Manoranjan says, 'give me a short break, i'll clean up and come back'
The last appearance of K.Balanchander, a legend, and a maker of world-class Tamil films.
The Hollywood film 'The Hero' starring Sam Elliott is inspired by the screenplay of Uthama Villain by Kamal Haasan.
Initial reports suggested that popular comedian Vivek would play an important role in the film, making the film his first collaboration with Kamal Haasan. The reports, however, went unconfirmed and eventually false.
The title "Uttama Villan" was given since the hero is "Uttaman"(Faithful man) to himself and a "Villan" to the society in real. The hero finishes his unfinished duties to everyone in tree of life and gives his last sacrifice of happiness to the entire world.