Jack Quaid, who plays Meg Ryan's son Marcus Macaulay, is her son in real life, from her marriage with Dennis Quaid.
Reunites Tom Hanks and Meg Ryan who previously worked together on Joe contro il vulcano (1990), Insonnia d'amore (1993) and C'è post@ per te (1998).
This movie is based on the book 'The Human Comedy' by William Saroyan. Meg Ryan read this while she was focusing on ways to cope with her divorce from Dennis Quaid.