The drawing of Sid (John Leguizamo) that Sid gave Brooke (Jessie J) is the same drawing that he draws on the wall in the first film.
Not counting spin-offs, this film makes Ice Age the first ever computer animated theatrical film franchise to feature five installments.
This is the longest movie in the franchise.
Sid speaks without a lisp for the first time in one of the scenes.
In the first L'era glaciale (2002) the animals encounter a cave with a UFO frozen in the ice. That was one of the inspirations for this film.