While editing the "Eye Vacuum Trap" scene, Steve Forner had local police called on him. According to editor Kevin Greutert, Forner was working on the scene in his office when the police knocked on the door, citing neighbors' concerns of someone being "tortured to death" inside.
In the film, John uses the e-mail address "kramerjohn994@gmail.com" to send an e-mail to Cecilia. This e-mail address works; viewers can send e-mails to this address. They will receive a reply stating that John is away but will reply when he becomes available again.
The first film in the series to not feature police investigating a murder.
In Saw VI (2009), there was a scene in which John was denied insurance coverage for an experimental cancer treatment located in Norway. In this film, he seeks the treatment out.
Lionsgate brought back their "red gears" logo for this film. The last time the logo was used in this series was in Saw 3D - Il capitolo finale (2010).