Greg Russo, who co-wrote Mortal Kombat (2021), told Collider he sees the reboot as a trilogy with the first film set before the tournament, the second film set during the tournament, and the third film set post-tournament.
Jessica McNamee has expressed interest in exploring Sonya's relationship with Johnny and Cassie Cage in potential sequels.
After the release of Mortal Kombat (2021), Simon McQuoid said the character Johnny Cage was not introduced in the film because Cage is a "giant personality" and would throw the film out of balance. He revealed that potential sequels could explore the material for characters like Cage and Kitana. He also expressed he would like to include more female characters.
Officially announced on 26 January 2022 with Moon Knight (2022) writer Jeremy Slater helming the script.