Dylan O'Brien originally went in to the auditions to read for the role of Scott but felt a better connection to the role of Stiles.
Many of the supposed wolf howls heard on the show are actually gorillas.
When Dylan O'Brien auditioned he brought a blank piece of paper and a link to two of his YouTube videos.
Orny Adams (Coach) revealed at the nine year reunion that he didn't read any of the full scripts after sometime in season two; he figured Coach wasn't supposed to know any of what was going on anyway.
According to creator Jeff Davis,Ragazzi perduti (1987), Buffy l'ammazzavampiri (1997) and the Spider-Man comics were huge influences on creating this series.