Marian Rivera is the second actress to portray two main characters--Dyesebel and Darna--of Mars Ravelo's classic comic novels. The first one is Vilma Santos.
The series brings Mars Ravelo's five villain characters from his original Darna comic: Darna's arch-nemesis Valentina, and Babaeng Impakta, Babaeng Tuod, Babaeng Linta and Babaeng Lawin.
Ricky Davao is the only actor to appear in all three GMA-7's adaptation of Mars Ravelo's graphic novels. He also appeared as Cesar Magtanggol in Captain Barbell (2006), and Juan Legaspi in Dyesebel (2008).
Rufa Mae Quinto is the only actor to appear in all three GMA-7's adaptation of Mars Ravelo's graphic novels. He appeared as the sea-witch Amafura in Dyesebel (2008) and, briefly, as the villain Aerobika in Captain Barbell (2006).