The first season takes place around November 2016, as shown by media coverage of the Trump vs Clinton Presidential election and campaign signs in people's yards throughout the season.
No snakes were actually killed during the making of this show.
Mentioned in Series One and dominating Series Two, Saw Palmetto, also known as Serenoa Repens, is a small very slow growing palm, typically growing to 2-3 meters maximum height around Florida. Plants can survive back to the days of Columbus, when it was first used to treat poisoning. In the modern day it is an unproven but considered safe alternative ingredient in the supplement industry, albeit not that expensive versus claims made by Craig!