Postponed three times due to the COVID-19 pandemic, finally premiering in December 2021. Filming actually ended two weeks before the outbreak reached Brazil.
Daniel Rezende described this sequel as "more emotional without being a dramatic show. The characters are growing up, so the movie is about it. We got to this thought, 'It's possible to grow up and remain a child' and this guided us.
One of two movies featuring a Mônica in the title to be in theaters in February 2022. The other was Eduardo e Mônica (2020).