KJ Smith makes an appearance as her character Andrea in the BET+ original series "Bruh," which is set in the same universe as "Sistas."
Pam, Karen's assistant at the beauty shop, is played by Beyoncé Knowles' cousin Angela.
According to BET's site, Madam ("All the Queen's Men") and Fatima ("Zactima" and "Sistas") are cousins. This further indicates that all three shows exist in the same universe.