The scene where Che takes the bazooka from his fellow soldier (who keeps missing) and blows up the barracks with his first shot, was meant to show Che miss once then hit the target on his second attempt, but the crew were losing light so they had him get it in one.
Was the second feature-length movie to be shot with the Red One Camera, the first being Che - Guerriglia (2008), which was shot first to help Benicio Del Toro's weight loss for the second film.
Benicio Del Toro chose Ryan Gosling to play Benigno 'Beni' Ramírez. Gosling met with the real Ramirez and learned some Spanish to prepare for role. But delays during pre-production caused Gosling to drop out of the project.
The film is a tribute to the Marxist notion of advancement through two conflicting ideas, known as dialectics, with its division into halves, with two tempos, two color schemes, two aspect ratios and two approaches to chronology. Each half focuses on a different revolution, both fundamentally the same in theory but vastly different in outcome.