Laura Silverman plays the younger sister of Sarah Silverman's character. In real-life, Laura is the older sister.
Sarah's pet dog, Doug, was played by Sarah Silverman's real-life pet dog, Duck.
The series was almost not renewed for a third season because Comedy Central and the producers could not agree on the budget. Cable network Logo agreed to help produce the third season.
On the wall in Steve and Brian's apartment can be seen a movie poster for director Rob Schrab's film Robot Bastard