A sequel was planned, where the Kingpin vowed revenge on the Punisher after destroying Fisk Industries (Level 11 in the game). Concept art for the game later surfaced online, showcasing Typhoid Mary, Elektra, Daredevil, and Deadpool as supporting characters while Nick Fury, Black Widow, and Bullseye were to return. The game was later cancelled when the production company THQ experienced financial struggles and later filed for bankruptcy.
The car that almost runs over the Punisher has the license plate "ASM 129", which is a reference to the Marvel Comic Amazing Spider-Man, issue #129. This issue is the debut of the character the Punisher. Also, it is a Florida license plate most likely in reference to The Punisher (2004) which is set in Florida, and from which Thomas Jane reprises the role of the titular character.
A useful game exploit can be found on the 'Funeral Home' level. If the player stands near to the door in the attic section, it is possible to shoot enemies in the back as they enter. They will spawn endlessly allowing the player to accumulate vast scores thanks to the multiplier system which exponentially increases your points during a particularly long kill streak. It is not uncommon for someone to amass hundreds of thousands of points in a single sitting by exploiting this feature.
In the first level, Punisher kills a drugdealer named Damage. In the comics, Damage (Jaime Ortiz) is a drugdealer leader of the Bunsen Burners who is transformed into a cyborg after getting accidentally crippled by Punisher's Van.
The Mobile version of the game was released in 2004, the same year the feature film The Punisher (2004) was released, which also starred Thomas Jane in the lead. The PlayStation 2, Xbox, and Microsoft Windows version was released in 2005.