Queen Latifah originated her character, Gina Norris, in La bottega del barbiere 2 (2004). Beauty Shop (2005) is a part of the same cinematic universe as the La bottega del barbiere (2002) franchise, but takes place in Atlanta, not Chicago.
The last Metro Goldwyn Mayer film to be released on VHS.
Djimon Hounsou and Kimora Lee Simmons started dating two years after this film's release, and had one son together. They broke up in 2012.
Gina's main inspiration in the film is Madam C.J. Walker. Octavia Spencer, who is credited as "Big Customer" (the lady who declines the cappuccino), would go on to portray Walker in the miniseries Self-made - La vita di Madam C.J. Walker (2020).
The video store next to Gina's Beauty Shop is called "The Big Picture", which is a nod to Il grande regista (1989), a film starring Kevin Bacon.