Deborah Foreman and Anthony Hickox were dating during the making of Waxwork - Benvenuti al museo delle cere (1988). They had, what Hickox describes as, a "messy break-up" prior to filming this movie so she declined the offer to reprise her role as Sarah.
Writer and Director Anthony Hickox offered Dolph Lundgren the part of Frankenstein's monster, but Lundgren turned it down.
(at around 1h 30 mins) Drew Barrymore was a friend of Anthony Hickox and was visiting the set the day they were shooting the vampire sequence. He decided to put her in the scene for a brief cameo appearance.
In the first film, Waxwork - Benvenuti al museo delle cere (1988), the Sarah Brightman character is wealthy and in this film she is dirt poor.
The same actor who plays the Nazi-obsessed lecturer in the first film, Buckley Norris, plays the Judge in this one.